Science
Mechanism of Action
This extract operates through a multifaceted biological pathway to enhance skin vitality. Its high concentration of phenolic compounds, anthocyanins, and flavonoids serves as a robust defense system, meticulously neutralizing free radicals and significantly mitigating oxidative stress at a cellular level. By protecting fibroblasts—the crucial cells responsible for synthesizing vital extracellular matrix components such as collagen, elastin, hyaluronic acid, and fibronectin—it directly contributes to maintaining the skin's structural integrity and elasticity. Furthermore, its flavonoid content is hypothesized to stimulate fibroblast proliferation and inhibit extracellular matrix metalloproteinases (MMPs), thereby actively promoting collagen renewal and contributing to the skin's conditioning and emollient properties.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
No data is available to suggest this ingredient is commonly dusted or to establish a dusting threshold.
The Formula
Formulation
Stability
As a hydrolyzed extract, it is generally water-soluble or dispersible. The stability of key components, particularly anthocyanins, can be influenced by several factors including pH, chemical structure, storage temperature, exposure to oxygen and light, presence of proteins, solvents, enzymes, and metal ions.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel assessed *Vitis vinifera (grape)-derived ingredients*, including 'hydrolyzed grape skin', concluding they are safe for use under current cosmetic practices. In vitro assays predicted 'hydrolyzed grape skin' to be non-irritating to eyes at concentrations exceeding 5 mg/ml (IC50 > 5 mg/ml in a neutral red uptake assay using fibroblast cultures). Furthermore, it did not elevate pro-sensitizing markers in an in vitro assay, indicating a low potential for immune cellular response stimulation. The FDA lists *Vitis Vinifera (Grape) Skin Extract* (enocianina) as an approved food color additive.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Hydrolyzed Vitis Labrusca Skin Extract offers valuable antioxidant, anti-inflammatory, and collagen-supporting benefits, making it a promising botanical for enhancing skin resilience and overall health.
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