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Moumoujus

HYDROLYZED ULVA PERTUSA EXTRACT.

Valuable / SKIN CONDITIONING

Hydrolyzed Ulva Pertusa Extract is a marine-derived active ingredient recognized for its profound skin revitalizing capabilities. It effectively stimulates the proliferation of human dermal fibroblasts and supports the integrity of the extracellular matrix, offering targeted benefits for aging skin.

Summary

Skin-conditioning agent Antioxidant Moisturizer/Humectant Collagen synthesis stimulator Glycosaminoglycan (GAG) synthesis stimulator MMP-1 inhibitor

Science

Mechanism of Action

This extract functions as a sophisticated skin conditioning agent by actively promoting the proliferation and enhancing the metabolic activity of human dermal fibroblast cells. It notably stimulates the biosynthesis of key extracellular matrix components, including type I and III collagens and vital glycosaminoglycans (GAGs). Furthermore, it demonstrates an inhibitory effect on matrix metalloproteinase-1 (MMP-1) in senescent fibroblasts, an enzyme implicated in collagen degradation, thereby supporting collagen homeostasis. Its inherent antioxidant properties also contribute to protecting skin cells from oxidative stress.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In a 72-hour in vitro study, a concentration of 250 µg/mL (0.025%) induced a significant 30% increase in the proliferation rate of pre-senescent and senescent human dermal fibroblast cells.
  2. 02 It was observed to inhibit the expression and secretion of matrix metalloproteinase-1 (MMP-1) in senescent fibroblasts, which is a crucial action for maintaining the skin's collagen structure and preventing its degradation.

Transparency

Dusting Analysis

Not commonly dusted

No specific data regarding dusting analysis for this ingredient is available.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

As a hydrolyzed extract derived from seaweed, Hydrolyzed Ulva Pertusa Extract is predominantly water-soluble. While the optimal pH for the extraction of its polysaccharides (ulvans) was identified as 6.57, a specific optimal pH range for its stability within cosmetic formulations has not been explicitly stated in the available research.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has not conducted a specific review for Hydrolyzed Ulva Pertusa Extract. However, it is generally listed as a cosmetic skin conditioning ingredient without GHS classification or hazard statements. Related ingredients, such as Hydrolyzed Ulva Lactuca Extract, have received 'LOW' ratings from EWG for concerns like cancer, allergies, and developmental toxicity, suggesting a broadly favorable safety profile for hydrolyzed Ulva extracts. Polysaccharides from Ulva species (ulvans) are also described as non-cytotoxic across various cell types.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Hydrolyzed Ulva Pertusa Extract is a valuable anti-aging ingredient, demonstrating efficacy in boosting fibroblast activity, supporting collagen and GAG synthesis, inhibiting collagen-degrading enzymes, and providing antioxidant protection, with a generally favorable safety profile.

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