Science
Mechanism of Action
This advanced botanical extract operates as a potent skin conditioning agent, significantly improving the skin's resilience and appearance. It bolsters the skin's intrinsic defense mechanisms against oxidative stress by enhancing Superoxide Dismutase (SOD) expression by 16% in human epidermal keratinocytes, particularly after UVB exposure. For superior moisturization, it increases Aquaporin-3 (AQP-3) expression by 50% in keratinocytes. Furthermore, the extract promotes skin elasticity and firmness by stimulating a 22% increase in Type I collagen (COL1A1) expression in human dermal fibroblasts. Its rich amino acid profile also supports keratinocyte regeneration, supplies vital nutrients, and ultimately contributes to the skin's self-renewal energy, decelerating the signs of aging.
Research
Clinical Evidence
High confidence2%
Key findings
- 01 Increased Superoxide Dismutase (SOD) expression by 16% in human epidermal keratinocyte cultures exposed to UVB, indicating enhanced antioxidant protection.
- 02 Increased Aquaporin-3 (AQP-3) expression by 50% in human epidermal keratinocyte cultures exposed to UVB, significantly improving skin moisturization.
- 03 Increased Type I collagen alpha 1 (COL1A1) expression by 22% in human dermal fibroblast cultures exposed to UVB, contributing to enhanced skin elasticity.
- 04 Enhanced regeneration of keratinocytes was observed in a wound healing assay, suggesting accelerated skin repair.
- 05 In an in-vivo study, application over 28 days resulted in an average reduction of crow's feet by 8.0% (up to 10.1%) and notable improvement in skin roughness.
Transparency
Dusting Analysis
There is no available data to indicate common dusting practices or specific dusting thresholds for Hydrolyzed Rye Phytoplacenta Extract.
The Formula
Formulation
Stability
This extract is typically provided in an aqueous solution, often combined with solvents such as butylene glycol and 1,2-hexanediol, which supports its stability in water-based cosmetic formulations.
Safety
Safety Profile
Hydrolyzed Rye Phytoplacenta Extract is generally regarded as safe for topical application in cosmetic products. The Cosmetic Ingredient Review (CIR) Expert Panel has not specifically evaluated this ingredient. While EWG Skin Deep rates it with 'LOW' concern for various health aspects, data availability is noted as 'Limited'. Due to a lack of specific data on topical usage during pregnancy and breastfeeding, consultation with a healthcare professional is recommended for these individuals. Adverse reactions are infrequent, but a preliminary patch test is always advisable to confirm individual skin compatibility.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Hydrolyzed Rye Phytoplacenta Extract is a valuable, science-backed ingredient offering comprehensive benefits for skin rejuvenation, notably enhancing hydration, elasticity, and antioxidant protection across all skin types.
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