Science
Mechanism of Action
This extract functions by exhibiting strong antioxidant activity, effectively neutralizing DPPH and ABTS free radicals and reducing reactive oxygen species to mitigate oxidative stress and lipid peroxidation. It demonstrates anti-inflammatory properties by modulating immune responses and decreasing pro-inflammatory cytokine secretion, such as interleukin-6. Furthermore, it delivers anti-aging benefits through the inhibition of collagenase and elastase, which are enzymes that degrade essential skin proteins, alongside reducing senescent cell accumulation and enhancing collagen synthesis. Its polysaccharides, including beta-glucans like 'pleuran', and phenolic compounds are key bioactive components contributing to its comprehensive effects, including promoting wound healing by boosting collagen production, neovascularization, and epidermal growth factor (EGF) intensity.
Research
Clinical Evidence
Medium confidenceN/A
Transparency
Dusting Analysis
Effective concentrations for skin benefits in cosmetic compositions begin at approximately 0.01%. Formulations containing this ingredient below 0.01% may not deliver the intended therapeutic effects.
The Formula
Formulation
Stability
The thermostability of polysaccharides within Pleurotus ostreatus extracts varies based on extraction methods and pH. Water extracts typically yield more thermostable polysaccharides compared to those obtained through alkaline or acidic solutions, with acidic fractions generally exhibiting lower stability than neutral ones.
Safety
Safety Profile
Pleurotus ostreatus extracts are generally considered safe for human consumption and topical application, aligning with EU regulations including the Novel Food Regulation (2015/2283). Cosmetic formulations containing up to 10% of this extract have been evaluated as safe and effective for skin applications, with a low irritancy potential.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Hydrolyzed Pleurotus Ostreatus Fruiting Body Extract is a valuable ingredient, offering comprehensive benefits from antioxidant protection and anti-aging properties to anti-inflammatory and wound-healing support across all skin types.
Related
Similar Ingredients
Finding similar ingredients…