Science
Mechanism of Action
HYDROLYZED PLATYCARYA STROBILACEA FRUIT EXTRACT acts through a multi-faceted mechanism to combat signs of skin aging. It exhibits potent free-radical scavenging activity, effectively neutralizing oxidative stress. The extract also demonstrates inhibitory effects on elastase, an enzyme responsible for elastin degradation, and suppresses the expression of matrix metalloproteinase-1 (MMP-1), which contributes to collagen breakdown. Crucially, it directly promotes the synthesis of type I collagen, a fundamental structural protein, enhancing skin firmness and elasticity. Additionally, studies on a related extract suggest potential for hair growth by modulating key growth factors such as SCF, IGF-1, and KGF, while suppressing TGF-β1.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Increased expression of type I collagen mRNA by up to 37% in normal human fibroblast cells at a concentration of 20 µg/ml (in vitro).
- 02 A clinical study demonstrated a statistically significant anti-wrinkle effect.
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
HYDROLYZED PLATYCARYA STROBILACEA FRUIT EXTRACT has not undergone specific safety review by the Cosmetic Ingredient Review (CIR), Scientific Committee on Consumer Safety (SCCS), or the FDA. Paula's Choice indicates the ingredient as 'Not rated' and currently under review. Similarly, The Good Scents Company reports 'Not determined' for oral, dermal, and inhalation toxicity for Platycarya strobilacea fruit extract.
Your Skin
Skin Compatibility
Our Assessment
Verdict
With compelling in-vitro evidence of collagen synthesis promotion and reported clinical anti-wrinkle efficacy, this extract offers valuable anti-aging benefits, pending more comprehensive safety and precise topical concentration data.
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