Science
Mechanism of Action
This ingredient operates by comprehensively supporting the skin's delicate microbiome and bolstering its barrier function. It directly addresses transepidermal water loss (TEWL) and inflammatory responses, resulting in improved hydration and reduced redness. Hydrolyzed Lactobacillus Ferment precisely modulates immune activity and stimulates antimicrobial peptide synthesis, while enhancing tight junction proteins critical for barrier integrity. Through its rich profile of bioactive compounds, including lactic acid and peptides, it promotes efficient cell renewal and contributes to collagen synthesis, thereby accelerating skin's natural repair processes. Furthermore, it exerts antimicrobial, antioxidant, and anti-inflammatory effects, effectively balancing the skin microbiome to minimize irritation, regulate oil production, and help maintain optimal skin pH.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 Formulations containing Lactobacillus Ferment Lysate at 1-10% concentration demonstrated decreased transepidermal water loss (TEWL), reduced redness, and improved skin hydration. These formulations also accelerated skin repair by promoting cell renewal and increasing collagen production.
- 02 Postbiotic creams featuring Lactobacillus ferment lysate (pH 6.00 ± 0.02) achieved clinically significant improvements in atopic dermatitis symptoms (SCORAD index) and notably reduced recurrence rates in pediatric patients.
- 03 Topical application of a postbiotic complex, including Lactobacillus ferment, resulted in 100% alleviation of sensitive scalp syndrome symptoms, such as itching, prickling, tightness, pain, dandruff, and burning, in female volunteers over a 4-week period.
Transparency
Dusting Analysis
The available research data does not indicate that Hydrolyzed Lactobacillus Ferment is commonly dusted, nor does it specify any dusting thresholds or associated inhalation risks.
The Formula
Formulation
Stability
Generally stable for up to approximately 1 year under normal use and storage, ideally at 23-25°C. This ingredient can be integrated into both aqueous systems and emulsions. To maintain its integrity, it should be protected from extreme temperatures and strong oxidizers.
Conflicts
- Strong oxidizers
Safety
Safety Profile
The Expert Panel for Cosmetic Ingredient Safety (CIR) has affirmed that Hydrolyzed Lactobacillus Ferment, along with related forms such as Lactobacillus Ferment Lysate, is safe for use in cosmetic formulations. Human Repeat Insult Patch Tests (HRIPTs) conducted at concentrations of 4-10% and EpiDerm™ assays performed on undiluted samples predicted non-irritating and non-sensitizing outcomes. It is important to note that this ingredient consists of beneficial byproducts of fermentation, not live bacteria, minimizing potential biological risks. While generally well-tolerated across various skin types, a patch test is advisable for individuals with exceptionally sensitive skin due to a minimal theoretical risk of allergic reaction.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Hydrolyzed Lactobacillus Ferment is a valuable postbiotic ingredient offering significant improvements in skin barrier function, hydration, and overall skin health through its microbiome-balancing and reparative properties.
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