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Moumoujus

HYDROLYZED JELLYFISH EXTRACT.

Valuable CAS - / HUMECTANT, SKIN CONDITIONING

Hydrolyzed Jellyfish Extract is a potent marine-derived ingredient, recognized for its comprehensive antioxidant capabilities and ability to enhance skin moisture retention. It actively supports the repair and maintenance of essential dermal protein structures, making it a valuable skin conditioning and anti-aging agent.

Summary

Moisturizer/Humectant Skin Conditioning Antioxidant Anti-aging Collagen Support Elastin Support Anti-inflammatory Photo-protection Antibacterial

Science

Mechanism of Action

This extract functions by delivering bioactive peptides that exhibit strong antioxidant and anti-inflammatory effects within the skin. It supports the repair of endogenous collagen and elastin protein fibers and helps maintain the crucial natural ratio of type I to type III collagen, offering protection against UV-induced damage (photoaging). The ingredient enhances the skin's moisture retention capacity, activates cells for wrinkle reduction, and promotes keratinocyte reactivation, alongside increasing involukrin and transglutaminase production.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 At 0.74 mg/mL, it exhibited 50% hydroxyl radical scavenging activity in vitro and protected HaCaT cells from H2O2-induced oxidative damage. EC50 values for scavenging superoxide anion and DPPH radical were 1.55 mg/mL and 1.99 mg/mL, respectively.
  2. 02 A concentration of 50 µg/mL increased endothelial cell proliferation (EA.hy926 endothelial cells) in vitro and provided protection against cholesterol-induced apoptosis and VE-cadherin downregulation.
  3. 03 In a study on UV-induced photoaging mice, Jellyfish Collagen Hydrolysate significantly improved skin moisture retention, repaired endogenous collagen and elastin protein fibers, maintained the natural ratio of type I to type III collagen, and enhanced immunity. This hydrolysate showed a superior protective ability compared to non-hydrolyzed jellyfish collagen.
  4. 04 When formulated in a niosome, jellyfish collagen hydrolysate demonstrated antioxidant activity (65.9% DPPH scavenging and 34.6% metal chelating activity) and robust antibacterial activity (up to 98.8% against Staphylococcus aureus), indicating its suitability for topical applications.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Solubility can vary with pH. Acid-soluble forms dissolve transparently in acidic solutions of pH 1-4, are insoluble in water at pH 4-10, and can disperse in alkaline conditions (pH 10 or more). Neutral-soluble jellyfish collagen is water-soluble across all pH ranges. Enzymatic hydrolysis during preparation typically occurs at pH 7.0-8.0.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Jellyfish-derived collagen exhibits high biocompatibility, a low risk of allergenic responses, and minimal potential for zoonotic disease transmission. Jellyfish peptides are generally noted for their excellent antioxidant activity and safety profile.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Hydrolyzed Jellyfish Extract is a valuable multi-functional ingredient, offering significant antioxidant, photo-protective, and skin-reparative benefits with a favorable safety profile.

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