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Moumoujus

HYDROLYZED HORSE UMBILICAL EXTRACT.

Insufficient Data / HUMECTANT, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

Hydrolyzed Horse Umbilical Extract is a refined biomaterial derived from equine sources, abundant in beneficial peptides, amino acids, and nucleic acids. It offers comprehensive skin benefits, targeting hyperpigmentation, fine lines, and overall skin vitality through enhanced barrier function and cellular regeneration.

Summary

Skin conditioning Anti-aging Antioxidant Anti-inflammatory Humectant UV protection (indirect) Collagen synthesis support Wound healing Skin elasticity enhancement Hyperpigmentation reduction Skin barrier reinforcement

Science

Mechanism of Action

This extract actively reduces melanin synthesis and content, thereby offering protection against UV-induced pigmentation. It strengthens the skin's barrier function by fostering the growth of beneficial Staphylococcus epidermidis and enhancing antimicrobial peptide expression in human epidermal keratinocytes. The ingredient also mitigates wrinkle formation by decreasing stratifin expression in aged human cultured epidermal cells, supporting crucial epidermal moisturization factors like filaggrin and serine palmitoyltransferase. Its rich composition of essential amino acids, anti-oxidative enzymes, and nucleic acids contributes to improved skin elasticity and anti-aging effects. Furthermore, horse placental peptides activate mitochondrial activity in human fibroblasts, promote type I collagen production, enhance fibroblast migration (suggesting wound healing), and exhibit potent antioxidant, UV protective, and anti-inflammatory properties.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

This hydrolyzed extract is generally expected to be water-soluble. A specific optimal pH range for its stability is not extensively documented; however, related horse cytochrome c demonstrates maximum thermodynamic stability between pH 8.0 and 9.5.

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Unknown

The European Commission's CosIng database suggests vigilance regarding entry 419 of Annex II to Cosmetics Regulation 1223/2009, which prohibits Category 1 and Category 2 animal by-products in cosmetic formulations. No direct SCCS opinion or specific CIR review for 'HYDROLYZED HORSE UMBILICAL EXTRACT' for cosmetic use has been identified. While the CIR Expert Panel noted 'Insufficient Data or Information' for Human Umbilical Extract (a related but distinct ingredient) in 2010, this does not directly apply. An FDA risk-based decision for PrecisePRP Equine, a veterinary horse-derived product, is not relevant to this cosmetic ingredient for human use.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While Hydrolyzed Horse Umbilical Extract presents promising benefits for anti-aging, hyperpigmentation, and skin vitality, the current availability of specific topical efficacy data and comprehensive safety assessments for cosmetic use remains insufficient for a definitive rating.

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