Science
Mechanism of Action
This extract, often referred to as hydrolyzed fish collagen or marine collagen, primarily functions as a potent humectant, effectively attracting and retaining moisture to significantly improve skin hydration. It delivers vital free amino acids, including glycine, proline, and hydroxyproline, which serve as essential precursors for the biosynthesis of new collagen and elastin fibers within the dermis. Furthermore, its collagen oligopeptides interact with fibroblast cell membrane receptors, thereby stimulating the production of additional collagen, elastin, and hyaluronic acid. This synergistic action contributes to enhanced skin elasticity, increased dermal density, and a visible reduction in the appearance of wrinkles and pores. The ingredient also exhibits antioxidant activity, providing protection against environmental damage and potentially aiding in maintaining skin water balance.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 Demonstrated significant improvements in facial skin moisture, a reduction in the appearance of pores and wrinkles, and noticeable skin brightening after at least 2 weeks of consistent application. The formulated serum had a pH of 7.7 and exhibited strong antioxidant activity.
- 02 Resulted in a slight, yet measurable, increase in skin hydration and elevated skin surface lipids within 12 hours of application.
Transparency
Dusting Analysis
Clinical evidence consistently demonstrates the topical efficacy of Hydrolyzed Fish Scale/Skin Extract in improving skin hydration, texture, and overall appearance, indicating it is not typically used for 'dusting' at ineffective concentrations in well-formulated products.
The Formula
Formulation
Stability
Hydrolyzed fish collagen exhibits high solubility in both cold and hot water, with its highest solubility observed around pH 7. It demonstrates robust thermal stability, allowing for effective incorporation across a wide pH spectrum. While viscoelasticity of collagen solutions is notably stable within pH 6-10, a general pH range of 5.0-6.5 is commonly cited for optimal formulation. A specific serum formulated at pH 7.7 maintained good stability over a 6-month period.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has concluded that hydrolyzed collagen, including fish-sourced variants, is safe for use in cosmetics, aligning with the general guidelines of the European Union's Cosmetics Regulation. Clinical studies confirm no skin irritation or phototoxicity at concentrations up to 50% in human subjects. Specifically, a 20% solution (fish scale-sourced) showed no sensitizing effects in a Human Repeat Insult Patch Test (HRIPT) with 50 subjects, and a 30% solution was deemed non-sensitizing in guinea pig tests. While considered to have a low allergic potential, individuals with a known fish allergy should exercise caution, although the manufacturing process typically removes water-soluble allergens, significantly reducing potential reactions.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Hydrolyzed Fish Scale/Skin Extract is a valuable ingredient for improving skin hydration, elasticity, and overall appearance, with robust safety data and broad compatibility across skin types.
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References
Sources
- mdpi.com ↗
- researchgate.net ↗
- nih.gov ↗
- cir-safety.org ↗
- biogena.com ↗
- koreamed.org ↗
- wellnex-collagen.com ↗
- cosmileeurope.eu ↗
- specialchem.com ↗
- purebulk.com ↗
- derpharmachemica.com ↗
- bendbeauty.com ↗
- dntb.gov.ua ↗
- atlantic-collagen.com ↗
- semnl.com ↗