Science
Mechanism of Action
This extract functions primarily as a potent humectant and an effective skin-conditioning agent, adept at binding and retaining vital water within the stratum corneum. Composed of low molecular weight amino acids such as glycine, proline, and hydroxyproline, along with beneficial peptides, it is hypothesized to stimulate dermal fibroblast activity. This stimulation, in turn, may enhance the natural synthesis of endogenous collagen, contributing to improved skin elasticity and structural integrity.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 A clinical investigation utilizing a serum formulation, balanced at a pH of 7.7 and incorporating Hydrolyzed Fish Collagen, demonstrated significant enhancements across multiple skin parameters. Subjects reported notable increases in facial skin moisture, a measurable reduction in the appearance of pores and wrinkles, and amelioration of UV-induced acne after a consistent application period of at least 2 weeks.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
This ingredient exhibits optimal stability within formulations across a pH range of 6.15 to 7.7. Specifically, preparations are well-suited for direct skin application at pH values between 6.15-6.58. Related gelatin hydrolysates demonstrate robustness across a broader pH spectrum, from 4 to 8. For cosmetic applications, advanced pretreatment and spray-drying processes are essential to effectively mitigate and eliminate any inherent fishy odor.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel thoroughly assessed Hydrolyzed Collagen, including fish scale-derived variants, concluding its safety for use in cosmetics in 1985, a finding reaffirmed in 2006. A 20% aqueous solution of fish scale-sourced Hydrolyzed Collagen (average molecular weight ~400 Da) proved non-sensitizing in a Human Repeat Insult Patch Test involving 50 subjects. Marine-derived collagen is inherently free from concerns regarding prions or terrestrial animal viruses. Furthermore, an oral LD50 estimated at greater than 2500 mg/kg body weight in rats for a 30% aqueous solution indicated no observable systemic toxicity or mortality.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Hydrolyzed Fish Scale Extract is a valuable, safe, and versatile ingredient proven to significantly boost skin hydration and reduce visible signs of aging.
Related
Similar Ingredients
Finding similar ingredients…
References
Sources