Science
Mechanism of Action
Hydrolyzed Cyperus Rotundus Root Extract exerts its benefits through a sophisticated molecular cascade. It significantly mitigates inflammation by inhibiting nitric oxide (NO) production and suppressing key inflammatory mediators such as interleukin 6 (IL-6), cyclooxygenase-2 (COX-2), interleukin-1β (IL-1β), and tumor necrosis factor-α (TNF-α). Its rich profile of bioactive compounds, including flavonoids, terpenoids, and saponins, contributes to its antioxidant activity and profound skin-soothing properties. Furthermore, this extract enhances skin barrier integrity and hydration by upregulating the expression of critical genes such as aquaporin-3 (AQP-3), hyaluronan synthase 2 (HAS-2), claudin-1 (CLDN-1), cadherin 1 (CDH1), filaggrin (FLG), and involucrin (IVL). Polysaccharides within the root also contribute to its moisturizing capacity. Preclinical data indicates an antiproliferative effect by decreasing keratinocyte hyperproliferation, and it may also offer anti-pigmenting effects via tyrosinase inhibition.
Research
Clinical Evidence
Medium confidenceN/A
Transparency
Dusting Analysis
The provided research does not contain information regarding a minimum effective concentration or common usage levels that would suggest this ingredient is frequently used in negligible quantities ('dusted').
The Formula
Formulation
Stability
Specific stability data for Hydrolyzed Cyperus Rotundus Root Extract is not detailed in the provided research; general considerations for botanical extracts should be applied.
Safety
Safety Profile
EWG Skin Deep® rates 'CYPERUS ROTUNDUS ROOT EXTRACT' with a 'LOW' concern across categories including cancer, allergies & immunotoxicity, and developmental & reproductive toxicity. Product warnings advise external use only, discontinuing use if rash occurs, and avoiding application on damaged skin or contact with eyes. Some formulations containing Cyperus rotundus oil or extract explicitly advise that it 'may cause allergic reactions in a small number of people' and is 'not suitable for use by children, pregnant or breast-feeding people.'
Your Skin
Skin Compatibility
Our Assessment
Verdict
With its robust anti-inflammatory, antioxidant, and barrier-supporting mechanisms, coupled with potential depigmenting and hair reduction benefits, this ingredient offers valuable multifunctional properties for diverse skin concerns, despite clinical data specifically for the hydrolyzed form being limited.
Related
Similar Ingredients
Finding similar ingredients…