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Moumoujus

HYDROLYZED CARRAGEENAN.

Valuable CAS 53973-98-1 / SKIN CONDITIONING

Hydrolyzed Carrageenan is a marine-derived polysaccharide fragment distinguished by its potent humectant and skin conditioning properties. It actively attracts and retains moisture, optimizing skin hydration and bolstering the epidermal barrier. Additionally, it serves as an invaluable excipient for refining product texture and stability.

Summary

skin conditioning humectant emollient viscosity controlling emulsion stabilizing film forming anti-inflammatory antioxidant

Science

Mechanism of Action

This ingredient functions primarily as a skin conditioning agent, actively contributing to epidermal health by binding and retaining moisture within the skin. As a hydrophilic compound, it significantly boosts skin hydration and supports the integrity of the skin's natural moisture barrier. Beyond its conditioning role, it acts as a versatile cosmetic excipient, providing viscosity control, emulsion stabilization, and film-forming capabilities to enhance product texture and overall stability. Emerging in vitro research further suggests potential antioxidant and anti-inflammatory activities, pointing towards broader dermatological benefits.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In in vitro studies, hydrolyzed kappa-carrageenan and iota-carrageenan enhanced cell proliferation and improved wound healing in human dermal fibroblast (HDF) and keratinocyte (HaCaT) cell lines. A notable decrease in nitric oxide (NO) production was also observed, indicating potential anti-inflammatory effects and relevance for managing inflammatory conditions. The bioactivities were found to be highly dependent on the molecular weight of the hydrolyzed carrageenan.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 6 – 9
0 7 14

Stability

Hydrolyzed Carrageenan exhibits optimal stability within neutral to slightly alkaline pH ranges, specifically between pH 6 and 9. It is known to undergo hydrolysis and destabilization under acidic conditions. Studies have shown destabilization and aggregation in emulsions at pH 3 and 5, with superior stability observed at pH 6 for iota-carrageenan. The pKa of the anionic sulfate groups, approximately pH 2, significantly influences its pH-dependent behavior.

Conflicts

  • Strongly acidic pH environments (below pH 6)

Safety

Safety Profile

CIR Status
Safe as used
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) panel has affirmed Hydrolyzed Carrageenan as safe for cosmetic applications. It is recognized on the FDA safe list and is permitted for use in personal care products by the European Cosmetics Directive. The Environmental Working Group (EWG) assigns a low-hazard rating of '1'. It is crucial to differentiate cosmetic-grade Hydrolyzed Carrageenan from 'degraded carrageenan' (poligeenan), which is a harmful form produced under harsh acidic conditions and is not utilized in cosmetic or food products.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Medium

Our Assessment

Verdict

Valuable

Hydrolyzed Carrageenan is a valuable ingredient for enhancing skin hydration, promoting barrier health, and improving formulation texture, with promising early evidence for anti-inflammatory and wound healing benefits.

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