Science
Mechanism of Action
This ingredient primarily functions as a potent skin conditioning agent, working to improve the appearance and feel of dry or compromised skin by minimizing flaking and restoring a healthy suppleness. Its mechanism involves polysaccharides that efficiently bind water, facilitating rapid skin penetration to deliver deep moisture and establish a protective barrier. Hydrolyzed Aloe Barbadensis Leaf also imparts soothing, calming, and anti-inflammatory benefits, effectively reducing redness and irritation. It supports accelerated cellular regeneration by promoting faster cell turnover, while simultaneously stimulating the production of collagen and hyaluronic acid to enhance skin elasticity and diminish the visibility of fine lines. Additionally, it provides antioxidant protection through vitamins C and E, and exhibits antimicrobial properties.
Research
Clinical Evidence
Low confidenceN/A
Key findings
- 01 A 0.3% (w/v) *fermented* extract of aloe leaf skin significantly increased collagen production by up to 125% and reduced MMP-1 secretion by up to 69.41% in UVb-irradiated human skin fibroblasts, suggesting anti-aging potential. It is important to note this study was conducted on a fermented extract, not specifically a hydrolyzed one.
- 02 Aloe Barbadensis leaf juice (at 95% concentration) demonstrated significant improvements in acne severity, skin hydration, and inflammation over an 8-week period, evidenced by a reduction in acne severity (GAGS scores from 12.5 to 5.4), enhanced skin hydration (Corneometer from 34.8 to 52.4), and decreased inflammation (DPM scores from 3.1 to 1.5). This study focused on the leaf juice, not specifically a hydrolyzed form.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Aloe vera gel is highly susceptible to oxygen degradation, necessitating rapid stabilization post-extraction. Maintaining an acidic pH, such as 3.57-3.74, is crucial for preserving its integrity and inhibiting microbial spoilage when combined with preservatives. As a water-based ingredient, proper storage in a cool, dry environment is essential to prevent degradation.
Safety
Safety Profile
The CIR Expert Panel has deemed Aloe Barbadensis-derived ingredients, including hydrolyzed forms, safe for cosmetic use, provided that anthraquinone levels do not exceed 50 ppm. Manufacturing processes typically include controls to ensure these levels remain safely below concerning thresholds. While anthraquinones can exhibit phototoxic properties, clinical investigations of aloe preparations demonstrate no phototoxicity at these low concentrations. There is no specific SCCS opinion directly addressing 'HYDROLYZED ALOE BARBADENSIS LEAF'. The FDA approves Aloe barbadensis as a natural flavoring substance in food, but does not mandate pre-market safety testing for cosmetic ingredients, instead regulating adulterated or misbranded products.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Hydrolyzed Aloe Barbadensis Leaf is a valuable ingredient, offering broad-spectrum skin conditioning, hydration, and soothing benefits with a low risk of irritation and comedogenicity, making it highly suitable for diverse skin types and formulations despite limited specific clinical studies for its hydrolyzed form.
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References
Sources