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HYDROGENATED RETINOL.

Valuable CAS - / SKIN CONDITIONING

Hydrogenated Retinol is a stabilized retinoid derivative engineered for enhanced skin conditioning and comprehensive anti-aging benefits, working to improve skin texture and tone with reduced potential for irritation.

Summary

Skin Conditioning Emollient Anti-aging Skin Brightening Texture Enhancer Pore Minimizer Acne Treatment Scar Healing

Science

Mechanism of Action

This retinoid derivative functions as a potent skin conditioning agent, primarily by stimulating hyaluronic acid production within dermal fibroblasts. This action contributes significantly to anti-aging effects through the activation of the extracellular matrix and normalization of skin tissue. Its multifaceted mechanism leads to improved skin texture, minimized pore appearance, mitigation of aging signs, reduction of dark spots, enhanced scar healing, overall skin brightening, and effective acne combat.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH 5 – 7
0 7 14

Stability

Hydrogenated Retinol exhibits superior stability against light, heat, and oxidation compared to conventional retinol. Optimal stability is observed within a slightly acidic to neutral pH range of 5.0 to 7.0. Formulations should minimize heat during processing, cooling below 40°C before addition. Incorporating antioxidants and anti-irritant ingredients, along with anhydrous systems or encapsulated emulsions, can further enhance stability.

Conflicts

  • Alpha Hydroxy Acids (AHAs) and Beta Hydroxy Acids (BHAs), including glycolic, lactic, and mandelic acids, due to pH incompatibility and elevated risk of over-exfoliation.
  • Benzoyl Peroxide, as it can induce oxidation reactions leading to retinoid degradation.
  • L-Ascorbic Acid (Vitamin C) when applied simultaneously; it is recommended to separate applications, such as Vitamin C in the morning and Hydrogenated Retinol at night.
  • Physical exfoliants, which should be avoided on evenings when Hydrogenated Retinol is applied.

Safety

Safety Profile

CIR Status
Unknown
Sensitization risk Moderate

Formal safety assessments by regulatory bodies such as CIR, SCCS, or FDA specifically for Hydrogenated Retinol are currently unavailable. However, safety evaluations for related retinoids (Retinol, Retinyl Acetate, Retinyl Palmitate) by the CIR Expert Panel deemed them safe, with SCCS guidelines suggesting safety at up to 0.05% Retinol Equivalent (RE) in body lotions and 0.3% RE in other leave-on and rinse-off products. A chemical supplier indicates no hazard classification for Hydrogenated Retinol.

Your Skin

Skin Compatibility

No Normal
No Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

As a stable and milder retinoid, Hydrogenated Retinol offers significant benefits for improving skin texture, tone, and addressing signs of aging, making it a valuable asset in sophisticated skincare formulations.

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