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HUMAN HAIR KERATIN.

Valuable / HAIR CONDITIONING, SKIN CONDITIONING

Human Hair Keratin, primarily utilized in its hydrolyzed form, is a sophisticated protein ingredient proven to significantly enhance skin health and resilience. It works to deeply hydrate, reinforce the skin's natural barrier, and stimulate regenerative processes for a visibly smoother and more elastic complexion.

Summary

Enhances Hydration Improves Skin Elasticity Stimulates Collagen Production Strengthens Skin Barrier Reduces Transepidermal Water Loss (TEWL) Accelerates Skin Repair Provides Anti-Aging Properties Acts as a Humectant Skin Conditioning Agent Film Forming Agent

Science

Mechanism of Action

Hydrolyzed human hair keratin comprises bioactive peptides that function as potent humectants, effectively drawing and retaining moisture within the skin to boost hydration and improve elasticity. It establishes a protective, conditioning film that fortifies the skin's intrinsic barrier, thereby minimizing transepidermal water loss and safeguarding against environmental stressors. These peptides further stimulate fibroblast activity, promoting increased collagen synthesis, which contributes to enhanced skin firmness and a reduction in the appearance of fine lines. Additionally, they optimize the lipid organization within the stratum corneum, ensuring robust barrier function, and supply essential amino acids to support cellular repair and mitigate inflammation.

Research

Clinical Evidence

High confidence
Effective range 0.5–5%
Optimal

5%

Key findings

  1. 01 Topical application shows superior hydration, up to 40% improvement in moisture retention, stimulation of collagen synthesis, enhanced barrier function, accelerated skin repair, and anti-aging properties.
  2. 02 In a hand cream study, demonstrated penetration into the skin, resulting in increased moisturization without adverse effects.
  3. 03 Clinically proven to be non-irritating and non-sensitizing on the skin.
  4. 04 Participants experienced a 12.5% reduction in transepidermal water loss and a 10.1% increase in skin elasticity.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 5.5 – 7.5
0 7 14

Stability

Hydrolyzed keratin is most stable and effective within a pH range of 5.5 to 7.5. Severe alkaline conditions (above pH 10.0) can lead to the degradation of its peptide chains. Its amphiphilic properties may offer modest interface stabilization and enhance product texture in formulations with primary emulsifiers.

Synergies

  • Primary emulsifiers (to enhance product texture)

Conflicts

  • Severe alkaline conditions (pH > 10.0)

Safety

Safety Profile

CIR Status
Safe as used
Max tested
25%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel concluded that Hydrolyzed Keratin and Hydrolyzed Hair Keratin are safe for use in cosmetics. Human studies indicate non-irritancy at concentrations up to 25%. However, in some isolated instances, a 10% concentration of hydrolyzed keratin has been noted to potentially cause acute urticaria or skin irritation.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Human Hair Keratin is a valuable ingredient, clinically proven to significantly enhance skin hydration, elasticity, and barrier function, offering broad anti-aging and repair benefits across multiple skin types with a low risk of irritation.

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