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HORDEUM VULGARE SPROUT EXTRACT.

Valuable CAS 85251-64-5 / ANTIOXIDANT, HUMECTANT, SKIN CONDITIONING

Hordeum Vulgare Sprout Extract is a multifaceted botanical ingredient rich in antioxidants, offering robust protection against environmental stressors. It deeply hydrates the skin while promoting cellular regeneration, contributing to a more youthful and resilient complexion. Its anti-inflammatory properties also soothe irritation and enhance skin barrier function.

Summary

Antioxidant Humectant Skin-Conditioning Agent

Science

Mechanism of Action

This extract functions primarily as a potent antioxidant, utilizing its high content of vitamins C and E, polyphenols, and flavonoids to neutralize free radicals, thereby mitigating oxidative stress that leads to premature aging and environmental damage. It enhances skin hydration by acting as a humectant, drawing and retaining moisture to improve plumpness and suppleness. The ingredient exhibits significant anti-inflammatory capabilities by reducing redness and soothing irritation, partly through modulating gene expression and decreasing the activation of IL-1 receptor accessory proteins. Furthermore, it stimulates collagen production and extracellular matrix (ECM) synthesis, vital for improving skin elasticity, firmness, and overall repair, while actively inhibiting matrix metalloproteinase 2 (MMP-2) and matrix metalloproteinase 9 (MMP-9) expression, which are enzymes known to degrade collagen and elastin.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In vitro studies demonstrated that young barley extracts at concentrations of 25, 50, and 100 µg/mL significantly enhanced the survival rate and accelerated migration of human skin fibroblasts exposed to UVB radiation. These extracts also stimulated DNA biosynthesis and effectively inhibited the expression of matrix metalloproteinase 2 (MMP-2) and matrix metalloproteinase 9 (MMP-9).
  2. 02 Murine B16F10 melanoma cells showed observed anti-melanogenic effects when treated with Hordeum vulgare L. barley sprout extract.

Transparency

Dusting Analysis

Not commonly dusted

No specific data within the provided research indicates that Hordeum Vulgare Sprout Extract is commonly dusted in formulations, nor is there information regarding a minimum effective concentration percentage for this specific ingredient in cosmetic products to establish a dusting threshold.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Conflicts

  • Individuals with gluten sensitivity should exercise caution, as barley and its derivatives naturally contain gluten.

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Low

The CIR Expert Panel found insufficient data to definitively determine the safety of Hordeum Vulgare Sprout Extract under cosmetic conditions, recommending 28-day dermal toxicity data. However, related ingredients such as Hordeum Vulgare Extract have been reported safe for use in leave-on products at concentrations up to 1.5%, with a 0.005% concentration in an eye cream showing no irritation for sensitive eyes. Malt extract, a broader barley derivative, is generally recognized as safe (GRAS) by the US FDA for animal feeds. A key consideration is the presence of gluten, which may affect individuals with gluten sensitivity.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Hordeum Vulgare Sprout Extract is a valuable ingredient, demonstrating significant antioxidant, hydrating, anti-inflammatory, and anti-aging benefits for all skin types, though regulatory safety data for this specific extract remains insufficient by CIR standards.

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