Science
Mechanism of Action
Hordeum Vulgare Juice functions primarily as a robust antioxidant, mitigating free radical damage and oxidative stress through its rich composition of vitamins C and E, β-carotene, chlorophyll, and phenolic compounds. It enhances skin hydration and suppleness as a humectant and emollient, while simultaneously calming irritation and reducing inflammation. The ingredient also contributes to skin barrier integrity, promotes elasticity, and has shown capacity to stimulate DNA biosynthesis in fibroblasts and inhibit melanin production for a more uniform complexion.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 In a UV-treated human skin fibroblast model, a water extract of young barley juice at 25 µg/mL demonstrated a 24% increase in fibroblast survival.
- 02 Both ethanolic and water extracts from young barley juice, at concentrations ranging from 25 to 100 µg/mL, were observed to increase DNA biosynthesis and cell cycle progression (S phase arrest) in normal human skin fibroblasts.
- 03 An oral formulation referencing young barley showed improvements in skin hydration, reduction in stratum corneum thickness, inhibition of hyaluronidase leading to increased hyaluronic acid levels, and decreased UV-induced wrinkle formation through reduced collagen degradation in in vitro tests and a hairless mouse model. It also lowered UVB-induced epidermal thickening by decreasing MMP-1 expression.
- 04 A methanolic barley grass extract exhibited an inhibitory effect on melanin biosynthesis in B16 melanoma cells.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Aqueous extracts are typically free from essential oils and common fragrance allergens. Formulators should note its inherent green pigmentation. Should cloudiness or precipitation manifest, filtration may be necessary to ensure product clarity.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has indicated 'insufficient data' for Hordeum Vulgare Juice and other barley-derived ingredients, stating that 'significant data needs remain' for a comprehensive safety assessment. No specific toxicity or carcinogenicity data have been identified or submitted for review.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Hordeum Vulgare Juice exhibits promising in vitro and animal model efficacy in antioxidant, soothing, and anti-aging applications, yet a definitive safety assessment by the CIR Expert Panel remains pending due to insufficient data.
Related
Similar Ingredients
Finding similar ingredients…