Science
Mechanism of Action
This extract functions through its rich profile of bioactive compounds, including flavonoids and phenols, which confer potent antioxidant activity, neutralizing environmental free radicals. It acts as an effective emollient, attracting and retaining moisture to visibly improve skin softness and elasticity. Furthermore, Hordeum Distichon Extract promotes skin regeneration, calms irritations, and strengthens the skin's natural barrier. Its ability to regulate sebum production while providing hydration makes it suitable for diverse skin conditions, contributing to smoother texture and anti-aging benefits by supporting firmness and reducing fine lines.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 In a Human Repeat Insult Patch Test (HRIPT) for a lotion, no dermal sensitization was observed, though a slight potential for dermal irritation was noted. When formulated into an eye cream, no irritation or sensitization was detected.
- 02 An HRIPT of a facial moisturizer at this concentration resulted in mild-moderate reactions in one subject, potentially attributable to prior exposure to other ingredients.
- 03 No visible clinical ocular irritation was observed when incorporated into a mascara.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Components of Hordeum Distichon Extract can be solubilized in both aqueous and oil-based systems, commonly utilizing eluents like water, butylene glycol, and glycerin. One study indicates that 'hordeumin,' a pigment from barley bran, demonstrated highest pigment retention at pH 5.0, suggesting potential stability considerations for specific constituents around this pH.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel concluded that there was insufficient data to determine the safety of Hordeum Distichon Extract (as a whole plant extract). This was primarily due to a lack of 28-day dermal toxicity data and comprehensive dermal irritation/sensitization data at maximum reported use concentrations, distinguishing it from barley seed-derived ingredients deemed safe. Clinical observations at 1.8% indicated a slight potential for dermal irritation, and case reports of contact urticaria and eczema have been associated with barley exposure in occupational settings.
Your Skin
Skin Compatibility
Our Assessment
Verdict
While exhibiting promising antioxidant, moisturizing, and soothing benefits suitable for various skin types, the Cosmetic Ingredient Review Expert Panel has deemed the available safety data insufficient, particularly regarding dermal toxicity and irritation at maximum use concentrations, warranting cautious formulation.
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References
Sources