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HOLARRHENA ANTIDYSENTERICA SEED EXTRACT.

Insufficient Data CAS 90045-74-2 / SKIN CONDITIONING

Holarrhena Antidysenterica Seed Extract is a botanical ingredient recognized for its comprehensive skin conditioning properties. It works to enhance skin hydration by supporting the natural barrier, resulting in a softer, smoother, and more supple complexion. Rich in bioactive compounds, it also offers potential antioxidant and anti-inflammatory benefits.

skin conditioning antioxidant anti-inflammatory

Science

This extract functions primarily as a skin conditioning agent, improving overall skin health and appearance. Its ability to support the skin's natural barrier aids in moisture retention, contributing to a smooth and supple feel. The presence of various alkaloids, including conessine, along with flavonoids and phenolic compounds, suggests potential antioxidant and anti-inflammatory actions that can further benefit skin well-being.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Both
Optimal pH N/A
0 7 14

Safety

CIR Status
Insufficient data
Sensitization risk Unknown

Generally considered safe for topical application in cosmetic formulations. However, formal Cosmetic Ingredient Review (CIR) or Scientific Committee on Consumer Safety (SCCS) assessments with established maximum concentrations for topical use are currently unavailable. While acute oral toxicity studies in rats showed safety up to 2000-3000 mg/kg body weight, high oral doses over prolonged periods caused hepatotoxicity. For topical application, potential side effects such as skin irritation, allergic reactions, redness, or itching are possible, therefore, a preliminary patch test is always recommended. Data regarding topical use during pregnancy and breastfeeding are insufficient, advising consultation with a healthcare professional.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Insufficient Data

This extract offers promising skin conditioning and potential antioxidant benefits, though further clinical research and formal safety reviews are needed for comprehensive assessment and to establish optimal usage parameters.


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