Science
Mechanism of Action
Hippophae Rhamnoides Kernel Extract operates through multiple biological pathways. Its rich antioxidant profile, encompassing vitamins and polyphenols, actively neutralizes free radicals, thereby protecting skin from oxidative stress and environmental aggressors. Essential fatty acids fortify the skin barrier, reduce transepidermal water loss, and boost hydration by up-regulating aquaporins and hyaluronan synthetases. Furthermore, it modulates inflammatory responses by decreasing histamine release and enhancing PPARs expression, while stimulating collagen synthesis promotes regeneration, wound healing, and improved skin elasticity.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 In an in vitro study, 0.00005% (500 ng/mL) sea buckthorn seed oil applied to UV-radiated human keratinocytes and fibroblasts maintained 100% cell viability. This concentration also demonstrated influence on lipid metabolism, activated Nrf2 antioxidant pathways, reduced lipid peroxidation, and showed anti-inflammatory effects by enhancing PPARs expression.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Hippophae Rhamnoides extracts have demonstrated stability for over 8 weeks in oil-in-water emulsions and can enhance SPF efficacy.
Conflicts
- May temporarily stain skin if used in high concentrations.
Safety
Safety Profile
While the Cosmetic Ingredient Review (CIR) has not specifically reviewed 'HIPPOPHAE RHAMNOIDES KERNEL EXTRACT', related Hippophae Rhamnoides Oil is generally considered safe and well-tolerated with low allergy risks. High concentrations of the oil may be mildly comedogenic and could temporarily stain the skin. EWG assesses this extract with low concerns across cancer, allergies & immunotoxicity, and developmental & reproductive toxicity.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Hippophae Rhamnoides Kernel Extract is a valuable multi-functional ingredient, offering significant antioxidant, anti-inflammatory, and regenerative benefits, particularly for dry and sensitive skin types.
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