Science
Mechanism of Action
This extract primarily functions as an antioxidant, actively preventing the oxidation and deterioration of ingredients by inhibiting oxygen-promoted reactions. Beyond this direct action, extracts from various parts of the Hippophae rhamnoides plant are recognized for broader dermatological benefits. These include supporting collagen synthesis (specifically up-regulating collagen type-III), enhancing the skin's natural antioxidant defense systems, and reducing lipid peroxide levels, particularly in wound healing. Furthermore, other Hippophae rhamnoides extracts have demonstrated an ability to mitigate skin dryness by increasing aquaporin 3 and hyaluronan synthetase 2 expressions, protect against oxidative stress, prevent cellular apoptosis, and soothe sensitive skin by decreasing histamine release. Callus culture methods specifically aim to maximize the yield of these beneficial active compounds.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) has not yet reviewed this ingredient for safety. General irritancy and comedogenicity data are currently unknown.
Your Skin
Skin Compatibility
Our Assessment
Verdict
HIPPOPHAE RHAMNOIDES CALLUS CULTURE EXTRACT is a valuable antioxidant ingredient with potential for broader skin benefits, though specific clinical efficacy and safety data for this particular extract type are currently limited.
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References
Sources