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Moumoujus

HIPPOPHAE RHAMNOIDES ACID.

Insufficient Data / EMULSION STABILISING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SURFACTANT - CLEANSING

HIPPOPHAE RHAMNOIDES ACID refers to acidic compounds naturally present within the nutrient-rich Hippophae Rhamnoides (sea buckthorn) plant. While specific isolated clinical data for this 'acid' is limited, the broader sea buckthorn fruit extracts and oils are widely recognized for their comprehensive array of essential fatty acids, vitamins, and potent antioxidants beneficial for skin health.

Summary

Antioxidant Anti-inflammatory Skin Barrier Support Hydration Skin Repair & Regeneration Antimicrobial

Science

Mechanism of Action

Sea buckthorn compounds, primarily found in its oil and fruit extracts, exhibit multi-faceted benefits. They act as robust antioxidants by preventing UV-induced reactive oxygen species (ROS) generation and stimulating the Nrf2 pathway, which boosts endogenous antioxidant enzyme activity and minimizes lipid peroxidation. Anti-inflammatory properties are evident through the enhancement of fibroblast PPARs, indicating a prevention of NF-κB-dependent inflammatory responses. Furthermore, the essential fatty acids contribute to a strengthened skin barrier, reducing transepidermal water loss (TEWL) and enhancing hydration. Specific fatty acids, such as palmitoleic acid, also support tissue repair, regeneration, and possess antimicrobial effects.

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Sea buckthorn seed oil, at a concentration of 500 ng/mL, demonstrated partial prevention of UV-induced reactive oxygen species (ROS) generation. It also elevated non-enzymatic antioxidants including glutathione (GSH), thioredoxin (Trx), and vitamins E and A in human keratinocytes and fibroblasts, alongside stimulating Nrf2 activity to enhance antioxidant enzyme function and reduce lipid peroxidation.
  2. 02 Palmitoleic acid, a principal fatty acid present in sea buckthorn pulp oil, exhibited efficacy at concentrations above 1.0 mg/ml in preventing the adherence of pathogenic yeast cells (C. albicans) to isolated mammalian stratum corneum sheets.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH 2.7 – 2.9
0 7 14

Stability

The Hippophae Rhamnoides fruit is naturally highly acidic, typically featuring a juice pH between 2.7 and 2.9, attributed to malic and quinic acids. Sea buckthorn components include both oil-soluble elements like fatty acids and fat-soluble vitamins (A, E, K), and water-soluble components such as Vitamin C and fruit acids. Specific stability data for 'HIPPOPHAE RHAMNOIDES ACID' as an isolated ingredient is not available; overall stability depends on the complex composition and processing of the extract or oil.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Information specifically for 'HIPPOPHAE RHAMNOIDES ACID' is not available. However, 'Hippophae Rhamnoides Fruit Extract' is generally deemed safe for cosmetic applications within recommended concentrations, presenting a low risk of allergic reactions and being non-comedogenic. Oral sea buckthorn supplements have been used safely for durations up to 90 days.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While extensive research supports the valuable skin benefits of comprehensive Hippophae Rhamnoides extracts and oils, specific clinical and safety data for HIPPOPHAE RHAMNOIDES ACID as a distinct, isolated compound remain largely undefined, warranting further dedicated study.

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