Science
Mechanism of Action
Rich in bioactive compounds such as flavonoids, phenolic acids, glycosides, and polysaccharides, Hibiscus Syriacus Callus Culture Extract functions as a robust antioxidant, anti-inflammatory, and skin protectant, effectively countering oxidative stress. It drives skin regeneration by stimulating the synthesis of fibronectin and collagen, alongside enhancing fibroblast contractility. The extract also optimizes skin hydration and barrier function by elevating the expression of aquaporin 3 and filaggrin genes, and includes natural alpha-hydroxy acids for gentle cellular turnover.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 In human fibroblast studies, the extract stimulated fibronectin synthesis by 16% and collagen synthesis by 60%, while increasing fibroblast contractility by 30%. Ex vivo studies on human injured skin biopsies showed accelerated wound healing and improved skin closure. Additionally, it boosted aquaporin 3 expression by 20% and filaggrin gene expression by 58%, significantly enhancing skin hydration and barrier function.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
This water-soluble extract performs optimally within a pH range of 5.6 to 7.0. It exhibits stability in formulations that are neutral to slightly acidic, consistent with the pH conditions observed during its plant cell culture.
Safety
Safety Profile
Generally considered safe for use in cosmetic formulations at recommended concentrations. However, individuals with known plant allergies or particularly sensitive skin are advised to exercise caution and perform a patch test prior to widespread application.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This potent plant stem cell extract is a valuable ingredient for promoting skin regeneration, enhancing hydration and barrier function, and providing comprehensive antioxidant protection.
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References
Sources