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Moumoujus

HEXYLOXYETHANOL.

Questionable CAS 112-25-4 / SOLVENT

HEXYLOXYETHANOL functions primarily as a versatile solvent and co-solvent within formulations, adept at dissolving a broad spectrum of substances including both hydrophilic and lipophilic compounds. While enhancing product stability and performance, its application in skincare requires stringent adherence to concentration limits due to significant irritancy concerns.

Summary

solvent co-solvent

Science

Mechanism of Action

As a potent solvent, HEXYLOXYETHANOL effectively solubilizes diverse components within a formulation. Its capacity to dissolve both water-soluble and oil-based substances facilitates the uniform dispersion of ingredients, thereby stabilizing the product matrix and optimizing the delivery of other compounds. It does not exert direct biological activity on the skin but enables the formulation's integrity.

Research

Clinical Evidence

Insufficient-data confidence
Effective range ≤10%
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

HEXYLOXYETHANOL exhibits general stability under controlled conditions but demands careful handling due to several incompatibilities. It is prone to hazardous reactions or decomposition when exposed to strong oxidizing agents, strong acids, strong bases, or reactive metals. Furthermore, it is air sensitive, with a risk of forming explosive peroxides upon contact with atmospheric oxygen, necessitating storage in tightly sealed, corrosion-resistant containers under inert gas, away from heat and direct sunlight.

Conflicts

  • strong oxidizing agents
  • strong acids
  • strong bases
  • reactive metals
  • atmospheric oxygen

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
10%
Sensitization risk High

The European Chemicals Agency classifies HEXYLOXYETHANOL as harmful upon skin contact and ingestion, capable of causing skin burns and serious eye damage, and notes it as a severe respiratory tract irritant. Animal studies corroborate severe skin irritation and ulceration. Despite its classification as an EPA Safer Choice 'green circle product' indicating low environmental concern, the significant irritation warnings necessitate its use in cosmetic and cleaning products at concentrations strictly below 10% to minimize public health risk.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Verdict

Questionable

While HEXYLOXYETHANOL offers potent solvent capabilities crucial for formulation stability, its classification as a severe irritant with corrosive potential, even at concentrations below 10%, makes its inclusion in precision skincare highly questionable due to significant safety concerns for skin.

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