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HEXENYLOXY-PROPANENITRILE.

Optional CAS 142653-61-0 / PERFUMING

HEXENYLOXY-PROPANENITRILE is a synthetic aroma compound primarily used in skincare to impart a complex, fresh bouquet of green, fruity, floral, and tropical notes to formulations.

Perfuming Agent

Science

This ingredient functions exclusively as a perfuming agent within cosmetic formulations, enhancing the sensory experience without directly impacting skin physiology.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

This ingredient is utilized for its perfuming properties rather than for purported skin benefits, thus it is not typically 'dusted' or misrepresented regarding its efficacy.


The Formula

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Exhibits excellent stability under normal formulation conditions, making it suitable for a broad spectrum of technical cosmetic applications.

Conflicts

  • Strong oxidizing agents
  • Strong acids
  • Strong bases

Safety

CIR Status
Not reviewed
Sensitization risk Low

The Expert Panel for Fragrance Safety (RIFM) concluded that 3-(cis-3-hexenyloxy)propanenitrile (a synonym) is safe as a fragrance ingredient under current declared levels of use. It is assessed as non-genotoxic and presents no safety concerns for skin sensitization, photoirritation, or photoallergenicity. The calculated Margin of Exposure (MOE) for repeated dose toxicity is >100, and the total systemic exposure (0.42 μg/kg/day) is below the Threshold of Toxicological Concern (TTC) of 1.5 μg/kg/day for a Cramer Class III material. No specific review by CIR or SCCS for cosmetic use was found, nor direct FDA status.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Optional

HEXENYLOXY-PROPANENITRILE serves purely as an optional perfuming agent, delivering fresh green and fruity notes with a low risk of irritation or sensitization based on comprehensive RIFM safety assessments.


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