Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle

HEXAPEPTIDE-47.

Valuable / SKIN CONDITIONING

Hexapeptide-47 is a sophisticated synthetic peptide engineered to deeply condition and hydrate the skin, while also offering significant soothing benefits. It actively mimics natural skin peptides, promoting enhanced cellular communication for optimal skin health and vitality.

Skin Conditioning Peptide Anti-Aging Skin Repair Moisturization Firmness Soothing Barrier Support Collagen Stimulation

Science

This synthetic hexapeptide, formed from a precise sequence of amino acids including glycine, histidine, proline, serine, and tryptophan, functions by emulating the skin’s inherent peptides. It fosters optimized cellular communication, which in turn reinforces the skin's natural moisture barrier, ensuring sustained hydration and protection against environmental stressors. Beyond its conditioning and soothing properties, Hexapeptide-47 has been observed to stimulate collagen synthesis, contributing to a reduction in the appearance of fine lines and wrinkles, and promoting a firmer, more elastic, and regenerated complexion.


Research

Medium confidence
Effective range 1–3%
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Hexapeptide-47 is typically formulated and supplied in a water and glycerin base, indicating good stability within such systems.


Safety

CIR Status
Not reviewed
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) has not yet assessed Hexapeptide-47. As a cosmetic ingredient, it is generally regulated for safety by the FDA but does not require pre-market approval. Its low irritancy profile suggests a favorable safety margin for topical application.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Hexapeptide-47 is a valuable multi-functional peptide, highly compatible with all skin types, offering significant benefits in hydration, anti-aging, and robust skin barrier support.


Related

Finding similar ingredients…