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Moumoujus

HEXAPEPTIDE-44.

Insufficient Data / SKIN CONDITIONING

Hexapeptide-44 is a foundational peptide that forms Nicotinoyl Hexapeptide-44 upon reaction with niacin. This derivative is a multi-functional ingredient, providing antioxidant benefits, skin protection, and signaling capabilities to support cellular repair and regeneration.

Summary

Antioxidant Skin Protecting Anti-aging Regenerating Firming

Science

Mechanism of Action

Nicotinoyl Hexapeptide-44, the active compound derived from Hexapeptide-44 and niacin, functions as a potent antioxidant by inhibiting oxygen-promoted reactions, thereby preventing oxidative damage and lipid rancidity. It also acts as a skin-protecting agent, bolstering the skin's resilience against harmful external influences. As a signaling peptide, it activates the body's inherent repair mechanisms, stimulating the regeneration of mature skin, enhancing its structural integrity, and contributing to a visible reduction in the appearance of wrinkles.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Unknown
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

No specific safety assessments from the Cosmetic Ingredient Review (CIR) or the Scientific Committee on Consumer Safety (SCCS), nor an FDA status, are available for Nicotinoyl Hexapeptide-44. However, EWG Skin Deep classifies Nicotinoyl Hexapeptide-44 with a 'LOW' hazard rating across various concerns, including cancer, allergies & immunotoxicity, and developmental and reproductive toxicity, suggesting a favorable safety profile.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Insufficient Data

Despite its encouraging antioxidant, skin-protecting, and regenerative mechanisms, comprehensive clinical data on Hexapeptide-44's efficacy and ideal concentrations remains to be established.

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