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HEXAPEPTIDE-40.

Valuable / SKIN CONDITIONING

HEXAPEPTIDE-40 is a biomimetic peptide designed to activate the skin's natural repair mechanisms. By mimicking crucial growth factors, it signals skin cells to bolster vital structural components. This action effectively enhances skin firmness, elasticity, and visibly diminishes the appearance of wrinkles.

Anti-aging Skin conditioning Moisturizing Evens skin tone Peptide

Science

This advanced peptide, often referred to as Nicotiana Benthamiana Hexapeptide-40 sh-Oligopeptide-1, functions by communicating with key receptor sites on the skin's surface. These signals stimulate natural repair processes, promoting cell regeneration and boosting the production of essential substances like collagen, elastin, and hyaluronic acid. The result is a comprehensive improvement in skin structure and reduced visible signs of aging.


Research

Medium confidence
Effective range 1–2%
Optimal

1.5%

Key findings

  1. 01 Consistent application of HEXAPEPTIDE-40 at a 1-2% concentration demonstrated measurable reductions in wrinkle depth, width, and volume.

Transparency

Not commonly dusted

No data suggests HEXAPEPTIDE-40 is frequently used at ineffective concentrations or as a 'dusting' ingredient.


The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Safety

CIR Status
Not reviewed
Sensitization risk Low

While formal CIR, SCCS, or FDA review for HEXAPEPTIDE-40 is not yet available, peptides generally exhibit a strong safety profile across all skin types. This ingredient is specifically noted as 'Teen SAFE', 'Baby SAFE', and 'Irritant Free' in product formulations, with adverse reactions being uncommon.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

HEXAPEPTIDE-40 is a valuable peptide that effectively targets signs of aging by supporting the skin's natural repair mechanisms, making it suitable for all skin types due to its low irritancy and comedogenicity.


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