Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

HEXAPEPTIDE-32.

Valuable CAS - / SKIN CONDITIONING

Hexapeptide-32, also identified as Acetyl Hexapeptide-32 or Tripeptide-32, is a sophisticated cellular messenger peptide designed to combat multiple signs of skin aging. It significantly enhances skin firmness, reduces wrinkle appearance, and boosts hydration, concurrently promoting a more uniform skin tone. This ingredient works by activating critical cellular pathways to achieve comprehensive skin rejuvenation.

Summary

Anti-aging Hydrating Skin-firming Collagen-boosting Elastin-boosting Brightening Antioxidant Anti-inflammatory Barrier support Cell-communicating

Science

Mechanism of Action

Hexapeptide-32 functions as a targeted cellular messenger, penetrating the skin's outermost layers to interact with specific cellular receptors. This interaction triggers a cascade of beneficial physiological responses, including a substantial increase in the production of collagen and elastin. It further strengthens the skin barrier by augmenting the synthesis of essential barrier proteins and lipids, regulates melanin production to address hyperpigmentation, and fortifies cellular defenses against oxidative stress and inflammation. The peptide also optimizes mitochondrial function, thereby improving energy metabolism within skin cells. While claims suggest it activates genes governing the skin's biological clock for day and night repair, independent research supporting these specific aspects is currently limited.

Research

Clinical Evidence

High confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Demonstrated 31% wrinkle reduction in clinical trials.
  2. 02 Achieved 27% increased skin firmness in clinical trials.
  3. 03 Provided 42% better hydration in clinical trials.
  4. 04 Stimulated fibroblasts up to 47% more effectively than previous peptides.
  5. 05 Resulted in a 38% reduction in hyperpigmentation after 8 weeks of regular application.

Transparency

Dusting Analysis

Not commonly dusted

No data available to suggest this ingredient is commonly 'dusted' or used below effective concentrations.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Hexapeptide-32 exhibits excellent stability across varying pH levels and is compatible with a broad range of other active ingredients. For optimal efficacy and shelf-life, products containing this peptide should be stored in a cool, dry place away from direct sunlight.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Specific safety assessments by CIR, SCCS, or FDA for Hexapeptide-32 (Acetyl Hexapeptide-32/Tripeptide-32) are not detailed in the provided data. However, peptides in general are recognized for their safety across all skin types, with this particular peptide noted to cause minimal irritation and no evidence of sensitizing, drying, or acne-causing effects.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Hexapeptide-32 is a valuable peptide, clinically proven to deliver significant anti-aging benefits, including wrinkle reduction, increased firmness, and enhanced hydration, alongside notable hyperpigmentation reduction, while maintaining broad skin compatibility and low irritation potential.

Related

Similar Ingredients

Finding similar ingredients…