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HEXAPEPTIDE-26.

Valuable CAS - / SKIN CONDITIONING

A sophisticated synthetic lipopeptide, HEXAPEPTIDE-26 offers a broad spectrum of benefits, including potent antimicrobial action against common skin bacteria. It effectively calms irritated skin, reduces redness, and minimizes blemishes through its anti-inflammatory properties, while also promoting the regeneration and strengthening of mature skin to diminish visible signs of aging.

Antimicrobial Anti-inflammatory Anti-aging Skin Calming Redness Reduction Skin Regeneration Skin Structure Strengthening Elasticity Enhancer

Science

As a cationic lipopeptide, Palmitoyl Hexapeptide-26 operates by stimulating biological functions within immune effector cells, thereby delivering broad-spectrum antimicrobial efficacy. It concurrently signals the skin to activate its endogenous repair mechanisms, fostering the regeneration of mature skin cells, reinforcing skin structure, and visibly mitigating the appearance of fine lines and wrinkles.


Research

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Demonstrates broad-spectrum antimicrobial activity against bacteria such as Escherichia Coli and Bacillus megaterium or Bacillus oleronius.
  2. 02 Acts as a skin de-stressor and anti-inflammatory agent, which helps to calm and rebalance irritated skin, reducing redness and blemishes.
  3. 03 Stimulates the regeneration of mature skin, strengthening its structure and visibly contributing to reduced wrinkles, improved complexion, and enhanced skin elasticity.

Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Safety

CIR Status
Insufficient data
Sensitization risk Unknown

Although a safety assessment for Palmitoyl Hexapeptide-26 was anticipated by the CIR as of 2013, and it was listed in the FDA's VCRP in 2012 for use as an antimicrobial in cosmetics, specific individual CIR safety conclusions or a maximum safe concentration are not directly available. However, broader CIR reviews for similar 'palmitoyl oligopeptides' have deemed them safe at low concentrations, suggesting a favorable safety profile within typical cosmetic applications.


Your Skin

No Normal
No Dry
No Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

HEXAPEPTIDE-26 is a valuable multi-functional ingredient, demonstrating significant antimicrobial, anti-inflammatory, and anti-aging properties beneficial for sensitive and mature skin, despite specific CIR safety data still being categorized as insufficient.


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