Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle

HEXAPEPTIDE-15.

Insufficient Data CAS - / SKIN CONDITIONING

HEXAPEPTIDE-15, also known as Palmitoyl Hexapeptide-15, is a synthetic peptide categorized as a skin conditioning agent. Its proposed function involves signaling the skin to activate its natural repair mechanisms, supporting cellular regeneration and overall skin structural integrity.

Skin Conditioning Skin Regeneration Support Structural Reinforcement Anti-aging (proposed) Complexion Improvement (proposed) Elasticity Enhancement (proposed)

Science

As a component of the broader peptide family, HEXAPEPTIDE-15 is understood to operate by interacting with the skin's biological processes, similar to endogenous protein building blocks. This interaction is hypothesized to signal the body to initiate and enhance the skin's intrinsic repair pathways. In mature skin, it is believed to stimulate cellular regeneration, reinforce skin structure, and contribute to visible improvements in wrinkle reduction, complexion evenness, and elasticity.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

Due to a lack of specific clinical efficacy data or recommended concentration ranges, it is not possible to determine if HEXAPEPTIDE-15 is commonly 'dusted' at sub-efficacious levels. Further research is required to establish its active concentration threshold.


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

No specific optimal pH range or detailed stability information is currently available for Palmitoyl Hexapeptide-15. However, peptides generally maintain greater stability within a moderate pH environment, as extreme pH values can accelerate degradation or hydrolysis.


Safety

CIR Status
Not reviewed
Sensitization risk Unknown

Comprehensive safety assessments by regulatory bodies such as CIR, SCCS, or FDA specifically for Palmitoyl Hexapeptide-15 are currently unavailable. While related peptides, such as Acetyl Hexapeptide-8, have been deemed safe by CIR up to 0.005%, and Hexapeptide-12 derivatives are considered safe below 10 ppm, these findings do not directly apply to HEXAPEPTIDE-15. Paula's Choice has noted this ingredient as 'Not rated' with 'no known benefits' and awaits further research review regarding its safety profile.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

HEXAPEPTIDE-15, or Palmitoyl Hexapeptide-15, currently lacks specific clinical studies and comprehensive safety assessments, resulting in insufficient data to confirm its efficacy or safety profile in skincare.


Related

Finding similar ingredients…