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HEXAPEPTIDE-11.

Valuable CAS - / SKIN CONDITIONING

Hexapeptide-11 is a signaling peptide engineered to enhance skin elasticity and firmness. It promotes the production of vital extracellular matrix components for a smoother, more resilient complexion.

Skin-conditioning Anti-aging Firming Elasticity Enhancer Antioxidant Support

Science

This peptide stimulates cellular activity, increasing oxygen consumption and upregulating genes for proteostasis and antioxidant responses. It boosts collagen, elastin, and hyaluronic acid synthesis, while also supporting skin barrier function and microbiome balance.


Research

High confidence
Effective range 1–5%
Optimal

2.8%

Key findings

  1. 01 An in-vivo study on 25 volunteers showed that a firming toner with 2.8% (v/v) Hexapeptide-11 solution, applied twice daily for 4 weeks, significantly improved skin's initial elastic response around the eyes and cheeks.
  2. 02 In-vitro studies indicate 2-5% (v/v) Hexapeptide-11 solution upregulates genes for proteostasis and antioxidant defenses, protecting cells from premature senescence.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 4.5 – 7
0 7 14

Stability

Optimal stability within pH 4.5-7.0. Incorporate into the aqueous phase below 40°C to maintain integrity.


Safety

CIR Status
Not reviewed
Max tested
0.01%
Sensitization risk Low

In-vitro studies show no significant toxicity in human fibroblasts. With a molecular weight of 676.8 Daltons, it is generally considered to pose a low risk for Type I allergies.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

Hexapeptide-11 is a valuable peptide for anti-aging and firming, offering robust support for skin elasticity, cellular health, and antioxidant defenses.


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