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HEXAHYDRO-TETRAMETHYL-SPIRODIOXOLANE-METHANONAPHTHALENE.

Questionable CAS 154171-77-4 / PERFUMING

This complex synthetic compound primarily functions as a perfuming agent in personal care formulations. While its direct mechanism on skin efficacy remains unexplored, it contributes to the sensory profile of products.

perfuming

Science

No specific mechanism of action or benefit on the skin has been elucidated in current research.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Safety

CIR Status
Not reviewed
Pregnancy
Caution
Sensitization risk Unknown

A safety assessment by the Research Institute for Fragrance Materials (RIFM) for this specific ingredient (CAS 154171-77-4) concludes its safety as a fragrance ingredient. Structurally similar compounds have been evaluated and found not to be genotoxic, PBT (Persistent, Bioaccumulative, and Toxic), photoirritating, or photoallergenic. One analogue demonstrated a No Expected Sensitization Induction Level (NESIL) of 5300 µg/cm² for skin sensitization. However, a Safety Data Sheet for a very closely related chemical (CAS 154171-76-3) classifies it as causing serious eye irritation and notes it is suspected of damaging fertility or the unborn child. This warrants extreme caution for use, especially in sensitive populations.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Questionable

Lacking any direct skincare benefits and presenting nuanced safety considerations due to a closely related chemical, its inclusion solely for perfuming is questionable for precision skincare formulations.


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