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Ingredient directory

Hexadec-7-en-16-olide

Hexadec-7-en-16-olide, also known as Ambrettolide, is a macrocyclic lactone primarily utilized in perfumery for its distinct warm, musky scent. This compound serves to impart a sophisticated aroma to a wide array of personal care and cosmetic products.

Directory entry · Individual source review pending

This profile is awaiting an individual source review. Treat its ratings, dose estimates and compatibility labels as provisional; they are not medical advice or proof of a finished product’s effects.

Fragrance

Science

This ingredient functions by interacting with olfactory receptors, thereby generating a characteristic musky aroma. Its role is solely to enhance the sensory profile of a formulation through scent, without providing direct physiological benefits to the skin.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH 3 – 10
0 7 14

Stability

Hexadec-7-en-16-olide demonstrates good stability across various matrices including lotions, shampoos, and soaps, as well as in alcoholic and functional fragrance systems. However, its stability is compromised by strong acids and highly alkaline conditions such as bleaches.

Conflicts

  • strong acids
  • strong alkalis (e.g., bleaches)
  • oxidizing agents

Safety

CIR Status
Safe with restrictions
Max tested
1%
Sensitization risk Low

The RIFM Expert Panel on Fragrance Safety has concluded that Ambrettolide is safe for use under specified conditions. According to IFRA standards, its maximum allowable concentration in facial moisturizers, creams, and toners is 1.00%.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Optional

Hexadec-7-en-16-olide is an optional ingredient, primarily valued for its musky fragrance, and is considered safe for cosmetic application when utilized within specified concentration limits.


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