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HEXACOSYL GLYCOL ISOSTEARATE.

Valuable / SKIN CONDITIONING, SURFACTANT - EMULSIFYING

HEXACOSYL GLYCOL ISOSTEARATE is a multifunctional ester acting as a skin conditioning and surfactant-emulsifying agent. It enhances product stability by facilitating the blend of oil and water, while also providing emollient benefits to the skin, promoting a smoother texture and reducing moisture loss.

Summary

skin conditioning emulsifying surfactant

Science

Mechanism of Action

This ingredient operates by lowering the interfacial tension between immiscible liquids, thereby enabling the formation of stable oil-in-water or water-in-oil emulsions. As an emollient, it integrates into the stratum corneum, effectively smoothing the skin's surface and establishing a protective barrier to minimize transepidermal water loss. It is also believed to possess humectant properties, attracting ambient moisture to the skin.

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Human studies on formulations containing 2-5% Glycol Stearate demonstrated no reported skin irritation or sensitization, indicating a generally mild profile for related glycol esters.
  2. 02 A repeated insult patch test involving 125 subjects exposed to 50% Glycol Distearate showed no evidence of irritation or hypersensitivity.
  3. 03 Primary skin irritation tests in rabbits using 1% Propylene Glycol Stearate, both with and without lidocaine, found no irritant response.

Transparency

Dusting Analysis

Not commonly dusted

No data available to suggest this ingredient is commonly 'dusted' or has a specific dusting threshold, as it primarily functions as a conditioning and emulsifying agent rather than a high-potency active.

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Related glycol isostearates exhibit chemical stability and resistance to oxidation, contributing positively to the longevity of formulated products. However, they may undergo hydrolysis under conditions of extreme pH or elevated temperatures.

Safety

Safety Profile

CIR Status
Safe as used
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has assessed and concluded that Glycol Stearate, Glycol Stearate SE, Glycol Distearate, and Propylene Glycol Isostearate (all related esters) are safe for use in cosmetics. Furthermore, Hexacosyl Glycol, a component of this ingredient, was deemed safe in a CIR assessment of 1,2-glycols. These comprehensive safety assessments of related compounds and components suggest a low risk profile for HEXACOSYL GLYCOL ISOSTEARATE.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

HEXACOSYL GLYCOL ISOSTEARATE is a valuable ingredient due to its multi-functional role in improving skin feel and product stability, supported by a low risk of irritation and comedogenicity inferred from related compounds.

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