Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle

HEPTAPEPTIDE-9.

Valuable CAS - / SKIN CONDITIONING

Heptapeptide-9, particularly in its N-acetylated form, is a cutting-edge biomimetic peptide designed to visibly diminish wrinkles and deep creases. By stimulating the skin's foundational repair mechanisms, it significantly contributes to a firmer, smoother, and more youthful complexion.

Skin Conditioning Anti-aging Collagen Boosting Elastin Boosting Skin Firming Wrinkle Reduction Skin Repair

Science

This advanced peptide functions by mimicking Transforming Growth Factor beta (TGFβ), a vital cytokine involved in skin recovery, wound healing, and immune defense. It actively stimulates dermal fibroblasts, prompting them to synthesize essential extracellular matrix components like collagen and elastin. This action not only enhances dermal cell metabolism but also signals the body to activate its endogenous repair processes, leading to profound skin rejuvenation.


Research

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In vivo tests involving Acetyl Heptapeptide-9 demonstrated a 55% reduction in wrinkles and deep creases.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Acetyl Heptapeptide-9 is a synthetic peptide modified with N-terminal acetylation, a process that significantly enhances its stability and compatibility within topical formulations. This engineered structure provides superior resistance to enzymatic degradation, ensuring consistent performance during manufacturing, storage, and application. It is typically supplied as a white to off-white lyophilized powder.


Safety

CIR Status
Not reviewed
Sensitization risk Low

While there is no specific CIR or SCCS safety assessment for Acetyl Heptapeptide-9 as a standalone cosmetic ingredient, it is generally considered safe for topical application. Limited data prevented an SCCS assessment for its nano colloidal gold complex. Although adverse reactions are uncommon, potential side effects such as skin irritation or redness may occur, making patch testing advisable for sensitive individuals.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Heptapeptide-9 is a valuable biomimetic peptide, clinically demonstrated to reduce wrinkles and deep creases by stimulating collagen and elastin production, making it a key active for advanced anti-aging formulations.


Related

Finding similar ingredients…