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HEPTAPEPTIDE-6.

Valuable CAS - / SKIN CONDITIONING

Heptapeptide-6 is a synthetic signaling peptide engineered to target multiple signs of aging by stimulating the skin's natural protective and regenerative processes. It contributes to a visibly smoother, firmer, and more radiant complexion through comprehensive cellular support.

Anti-aging Antioxidant Anti-inflammatory Skin-conditioning Promotes collagen synthesis Improves skin elasticity Reduces wrinkles Protects telomeres Promotes cell growth and proliferation

Science

This precision peptide operates on several fronts to enhance skin health and resilience. It actively stimulates collagen production, a key structural protein, which improves skin texture and elasticity while minimizing the appearance of fine lines and wrinkles. Functioning as a potent antioxidant, Heptapeptide-6 helps neutralize free radicals and mitigate damage from environmental aggressors like UV radiation. A core aspect of its action involves increasing the expression of Telomeric repeat-binding factor 1 (TRF1) protein, a component of the Shelterin complex that safeguards telomeres, thereby contributing to cellular longevity and combating intrinsic aging. Furthermore, it boosts catalase, an antioxidant enzyme crucial for protecting dermal cells from oxidative stress, and reduces Interleukin-8 (IL-8) levels to modulate inflammation. The peptide also promotes vital skin cell growth and proliferation, supporting the creation of a robust dermal network by aiding elastin and other structural proteins, and is associated with the down-regulation of matrix metalloproteinases (MMPs) that degrade collagen.


Research

Medium confidence
Effective range N/A
Optimal

0.014%


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Heptapeptide-6 is noted for its excellent solubility and stability in aqueous solutions. Specific optimal pH ranges for maintaining peak stability are not detailed in the provided research data.

Synergies

  • Antioxidants
  • Other peptides
  • Postbiotics
  • Botanical extracts

Safety

CIR Status
Not reviewed
Sensitization risk Low

Heptapeptide-6 has not been formally reviewed by the Cosmetic Ingredient Review (CIR), Scientific Committee on Consumer Safety (SCCS), or FDA. However, it is classified as 'Irritant Free' by SkinSAFE, and supplier data indicates 'no heavy metals, no skin and eye irritation', suggesting a favorable safety profile based on available information.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Valuable

Heptapeptide-6 is a valuable multi-functional peptide, offering significant anti-aging, antioxidant, and protective benefits suitable for a wide range of skin types with a low risk of irritation.


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