Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle

HEPTAPEPTIDE-14.

Valuable / SKIN CONDITIONING

Heptapeptide-14, frequently utilized as Copper Palmitoyl Heptapeptide-14, is a sophisticated peptide engineered to bolster skin's structural integrity. It actively stimulates the synthesis of collagen and elastin, critical proteins for maintaining skin firmness and elasticity, yielding visible anti-aging benefits. Clinical data indicates its potential to significantly reduce wrinkle appearance and enhance skin resilience.

anti-aging skin conditioning cell-communicating skin-identical ingredient

Science

This peptide operates by promoting the gene expression of both collagen and elastin within dermal fibroblast cells. This targeted stimulation leads to an increased natural production of these vital proteins, crucial for skin's firmness and elasticity. Its efficacy is often enhanced through advanced 'Cosmetic Drone' delivery systems, which precisely guide the encapsulated peptide to fibroblast receptors, also offering support for natural skin regeneration and defense against environmental stressors.


Research

Medium confidence
Effective range N/A
Optimal

0.001%

Key findings

  1. 01 After 28 days of daily use, participants experienced an average of 33% reduction in wrinkle surface area and a 19% increase in skin elasticity.

Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

The palmitoyl modification of Heptapeptide-14 significantly increases its lipophilicity, making it oil-soluble. Optimal delivery and efficacy in cosmetic formulations are frequently achieved through advanced encapsulation systems, such as 'Cosmetic Drones' utilizing biocompatible polymers like Lactic Acid/Glycolic Acid Copolymer or Polyvinyl Alcohol.

Synergies

  • Advanced delivery systems (e.g., Cosmetic Drone technology) to enhance targeted delivery and efficacy.

Safety

CIR Status
Not reviewed
Sensitization risk Low

While Heptapeptide-14 or Copper Palmitoyl Heptapeptide-14 has not undergone specific review by the Cosmetic Ingredient Review (CIR), related peptides are generally considered safe at low use concentrations (typically below 10 ppm). Its 'Irritant Free' classification by SkinSAFE further suggests a favorable safety profile.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Heptapeptide-14 is a valuable anti-aging peptide that significantly improves skin elasticity and reduces wrinkles by stimulating collagen and elastin synthesis, demonstrating a favorable safety and compatibility profile across all skin types.


Related

Finding similar ingredients…