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Moumoujus

HEMIDESMUS INDICUS ROOT POWDER.

Valuable CAS 90045-62-8 / SKIN CONDITIONING

Hemidesmus Indicus Root Powder is a botanical ingredient recognized for its comprehensive benefits, primarily functioning as a potent anti-inflammatory, antioxidant, and antimicrobial agent. It effectively soothes irritated skin, protects against oxidative stress, and helps manage bacterial proliferation, contributing to overall skin health and repair.

Summary

skin conditioning anti-inflammatory antioxidant antimicrobial skin healing

Science

Mechanism of Action

This ingredient operates through several key mechanisms: its anti-inflammatory properties help to calm irritation and diminish skin redness. It acts as an antioxidant by neutralizing harmful free radicals, thereby protecting skin cells from oxidative damage. Furthermore, Hemidesmus Indicus Root Powder exhibits antimicrobial activity, specifically inhibiting the growth of bacteria like *P. acnes* and *S. epidermidis*, which are often associated with acne conditions. It is also noted for its contributions to skin healing and wound recovery.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

2%

Key findings

  1. 01 A small-scale clinical observation in 2019 reported that a topical gel containing 2% Hemidesmus Indicus Root Powder led to a reduction in redness and itching within two weeks for patients suffering from eczema, acne, and minor burns.
  2. 02 In an in vitro study by Kumar and coworkers, a Minimum Inhibitory Concentration (MIC) of 0.051 mg/ml was established against *P. acnes* bacteria.
  3. 03 An in vitro study by Kumar and coworkers identified a Minimum Inhibitory Concentration (MIC) of 1.25 mg/ml against *S. epidermidis* bacteria.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

The dried roots are processed into a stable fine powder, which integrates readily into formulations. It is particularly well-suited for water-based preparations such as decoctions and pastes.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

No specific cosmetic safety reviews by CIR, SCCS, or FDA were identified. Research indicates Hemidesmus Indicus root extract is safe in animal models, demonstrating no severe behavioral or physiological damage at acute and sub-chronic doses up to 2000 mg/kg. Acute toxicity testing of the root powder suspension in Swiss albino mice showed no lethality or notable behavioral changes. The raw plant material (root) adheres to WHO standards for being free from microbial load, ensuring its suitability for formulation. It is important to distinguish that high oral doses (25%) of the dried stem, a different plant part, have shown hepatotoxic activity in animal studies, which is not relevant to the topical application of root powder.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Hemidesmus Indicus Root Powder is a valuable botanical ingredient offering robust anti-inflammatory, antioxidant, and antimicrobial properties, making it beneficial for a wide range of skin concerns, particularly for calming irritation and supporting overall skin health.

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