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HEMIDESMUS INDICUS ROOT EXTRACT.

Valuable CAS 90045-62-8 / SKIN CONDITIONING

Hemidesmus Indicus Root Extract, derived from the Indian Sarsaparilla plant, is a botanical ingredient recognized for its extensive benefits in skincare. It delivers a potent combination of antioxidant, anti-inflammatory, and antimicrobial actions, making it a valuable asset for maintaining skin health and addressing specific concerns like acne.

Antioxidant Antimicrobial Antibacterial Anti-inflammatory Soothing Detoxifying Wound Healing

Science

This extract functions as a robust antioxidant by neutralizing various free radicals, thereby protecting the skin from oxidative stress. It also exhibits anti-inflammatory properties, potentially mitigating inflammation by reducing reactive oxygen species and key inflammatory cytokines such as IL8 and TNFα. Furthermore, it demonstrates broad-spectrum antimicrobial activity against common skin pathogens including P. acnes and S. epidermis, alongside other bacteria and fungi, while supporting detoxification and wound healing processes.


Research

Medium confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The available research does not suggest this ingredient is commonly used at negligible concentrations for marketing purposes. Efficacy studies indicate specific concentrations for observable effects.


The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Aqueous extracts show high solubility, and the ingredient also dissolves effectively in polar solvents like methanol. Studies have utilized the extract at pH 7.4 and pH 8.0, suggesting stability within neutral to slightly alkaline environments, though a specific optimal pH range for formulation stability is not explicitly defined.


Safety

CIR Status
Not reviewed
Sensitization risk Low

Formal safety assessments by regulatory bodies such as CIR, SCCS, or FDA for cosmetic application are not available. While some studies mention potential hepatotoxicity with very high internal doses or specific stem extracts, these are not directly applicable to topical use of the root extract. It is generally regarded as safe for topical application, with Incidecoder reporting low irritancy and comedogenicity.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

This root extract offers a multifaceted approach to skin health, combining potent antioxidant, anti-inflammatory, and antimicrobial properties with good tolerability for diverse skin types.


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