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Moumoujus

HEMIDESMUS INDICUS EXTRACT.

Valuable / SKIN PROTECTING

Hemidesmus Indicus Extract, derived from the roots of the Indian Sarsaparilla plant, is a multifaceted botanical ingredient celebrated for its comprehensive contributions to skin health. It offers significant antioxidant, anti-inflammatory, and antimicrobial benefits, making it particularly effective for soothing irritation, combating acne, and protecting against environmental damage.

Summary

Antioxidant Anti-inflammatory Antimicrobial Antibacterial Detoxifying Wound Healing Skin Protecting Skin Conditioning

Science

Mechanism of Action

Hemidesmus Indicus Extract employs several mechanisms to enhance skin wellness. It exhibits potent antioxidant properties by inhibiting various types of free radicals, safeguarding skin cells from oxidative stress. Its anti-inflammatory activity is partly mediated by reducing reactive oxygen species and modulating inflammatory cytokines such as IL8 and TNFα. The extract also demonstrates antimicrobial and antibacterial effects against common skin pathogens like Propionibacterium acnes and Staphylococcus epidermis. Furthermore, it supports skin detoxification by aiding in the removal of metabolic waste, and is noted for its wound healing capabilities and overall skin protection.

Research

Clinical Evidence

Medium confidence
Effective range ≥2%
Optimal

2%

Key findings

  1. 01 Topical application of a 2% root extract gel reduced redness and itching within two weeks in a small-scale clinical observation.
  2. 02 Roots of Hemidesmus indicus showed a strong inhibitory effect on Propionibacterium acnes (P. acnes) with a Minimum Inhibitory Concentration (MIC) of 0.051 mg/ml.
  3. 03 Roots of Hemidesmus indicus showed a strong inhibitory effect on Staphylococcus epidermis (S. epidermis) with a Minimum Inhibitory Concentration (MIC) of 1.25 mg/ml.
  4. 04 A terpenoidal fraction from Hemidesmus indicus showed potent anti-acne activity, inhibiting both P. acnes and S. epidermis at a Minimum Inhibitory Concentration (MIC) of 38 ug/ml.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

No specific safety assessments by CIR, SCCS, or FDA were found in the provided research. Hemidesmus Indicus Extract is not among the ingredients for which FDA's Voluntary Cosmetics Reporting Program has reported uses, which often leads to 'no further action needed' by CIR for ingredients not in current widespread use.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Hemidesmus Indicus Extract is a valuable botanical ingredient offering a broad spectrum of benefits, including antioxidant, anti-inflammatory, and antimicrobial properties, making it suitable for a variety of skin concerns.

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