Science
Mechanism of Action
This unique glycoprotein, also known as Pseudoalteromonas Ferment Extract or Antarcticine, operates through several key pathways. It confers cryo-protective properties by modifying ice crystal formation, thereby preserving skin moisture and mitigating dryness and redness in cold environments. The extract significantly promotes skin cell regeneration by stimulating the synthesis of critical structural proteins like Collagen I, Collagen IV, and elastin, leading to enhanced skin elasticity, improved firmness, and a reduction in wrinkle depth. It forms a protective, moisture-retaining barrier on the skin's surface, effectively preventing transepidermal water loss and reinforcing the natural barrier function against environmental stressors. Additionally, it offers soothing, anti-inflammatory, and antioxidant benefits, aids in wound healing by stimulating fibroblast adhesion, and regulates sebum production to minimize shine and pore visibility by modulating the Melanocortin 5 receptor.
Research
Clinical Evidence
High confidence5%
Key findings
- 01 At a 1% concentration, in-vivo studies demonstrated a 14.8% increase in skin hydration, particularly beneficial in cold weather conditions.
- 02 A 5% concentration significantly reduced the depth of wrinkles around the eyes by 44% in manufacturer in-vivo tests.
- 03 In cellular studies, a 5% concentration boosted Collagen I production by 128% after 15 days, simultaneously increasing Collagen IV by 81% and elastin by 31% over the same period.
- 04 Unspecified concentrations have shown significant hydration improvements, including a 26% increase after four weeks and up to a 45% increase in moisture content within one week.
- 05 Further clinical observations indicate a doubling of collagen content and a 17% increase in elastin within two weeks, alongside a significant reduction in fine lines and crow's feet over 28 days of continuous use.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
This ingredient maintains stability across a pH range of 3.0 to 7.5, with optimal performance observed between pH 5.5-6.5. For emulsion formulations, it should be incorporated during the cool-down phase, specifically below 40°C (104°F). When formulating gels, it is best integrated into the water phase.
Conflicts
- Highly concentrated acids
- Potential to trigger Malassezia folliculitis in some individuals, a general consideration for ferment extracts.
Safety
Safety Profile
Pseudoalteromonas Ferment Extract (Antarcticine) is widely regarded as safe, non-toxic, and non-irritating for topical application, including on sensitive skin. It has successfully undergone human cell culture and topical use tests without eliciting skin irritation.
Your Skin
Skin Compatibility
Our Assessment
Verdict
HEMICHLORIS ANTARCTICA EXTRACT is a valuable multi-functional ingredient, clinically proven to enhance hydration, boost collagen and elastin, and significantly reduce wrinkles across all skin types.
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References
Sources