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Moumoujus

HELICHRYSUM STOECHAS CALLUS CULTURE LYSATE.

Valuable CAS 2251702-08-4 (generic) / HUMECTANT, SKIN CONDITIONING

This advanced botanical extract is derived from the callus culture of Helichrysum stoechas, a resilient plant known for its restorative properties. It is engineered to significantly enhance skin hydration, fortify the skin barrier, and actively resolve inflammation, making it particularly beneficial for dry and sensitive skin types.

Summary

Humectant Skin Conditioning Anti-inflammatory Barrier Repair

Science

Mechanism of Action

HELICHRYSUM STOECHAS CALLUS CULTURE LYSATE operates by boosting the number of lacunae, which are critical extracellular water reservoirs within the stratum corneum, thereby amplifying skin moisturization. Beyond hydration, it actively engages in resolving inflammation and restoring robust barrier function and homeostasis by decreasing pro-inflammatory mediators while simultaneously increasing pro-resolutive mediators, effectively interrupting the 'Inflamm'dryness™' cycle.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

1%

Key findings

  1. 01 A 1% concentration was shown to increase skin hydration by 32% compared to placebo and elevate lacunae (extracellular water tanks in the Stratum corneum) by 82% within five days. This contributes to improved skin barrier function, restored homeostasis, and resolution of inflammatory processes.

Transparency

Dusting Analysis

Not commonly dusted

No data is available to suggest this ingredient is commonly underdosed in formulations or to establish a 'dusting threshold'.

The Formula

Formulation

Solubility
Water
Optimal pH 4 – 4.5
0 7 14

Stability

The ingredient is acidified to a pH between 4 and 4.5 during its manufacturing to ensure color stability.

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Moderate

The Cosmetic Ingredient Review (CIR) has classified ingredients containing Helichrysum stoechas lysate with 'Insufficient Data' for a comprehensive safety evaluation. While there are general cautions from third-party sources about ingredients with insufficient data potentially causing irritation or having formulation issues, these are not specific to the inherent properties of this particular ingredient.

Your Skin

Skin Compatibility

No Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

This ingredient offers significant hydration, barrier repair, and anti-inflammatory benefits, making it a valuable addition for formulations targeting dry and sensitive skin, despite the current 'insufficient data' status from CIR.

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