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Moumoujus

HEDERA RHOMBEA EXTRACT.

Insufficient Data / HUMECTANT, SKIN CONDITIONING, SKIN PROTECTING

This botanical extract, derived from Hedera rhombea, is rich in triterpene saponins, conferring a range of potential benefits. It exhibits antioxidant and anti-inflammatory properties, while also acting as a natural cleanser and astringent for skin purification.

Summary

Antioxidant Anti-inflammatory Astringent Cleansing Antimicrobial Sebum Control Circulation Enhancer Skin Conditioning

Science

Mechanism of Action

Hedera rhombea extract's activity is primarily attributed to its triterpene saponins, which provide antioxidant and anti-inflammatory benefits. These compounds also function as natural cleansers and astringents, aiding in skin purification and pore refinement. For oily skin, similar saponins from related Hedera species have been observed to inhibit 5α-reductase, an enzyme crucial for sebum production, and contribute to antimicrobial action. In sensitive skin, compounds like alpha-hederin and hederacoside C may stabilize mast cells, thereby reducing inflammatory responses. Furthermore, the extract has demonstrated the ability to inhibit fungal biofilm formation and may enhance microcirculation, improving nutrient delivery and detoxification.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Inhibition of Candida albicans biofilm formation at an IC50 of 12.5 µg/mL.
  2. 02 Inhibition of Candida tropicalis var. tropicalis biofilm formation at an IC50 of 25 µg/mL.
  3. 03 Inhibition of Candida parapsilosis var. parapsilosis biofilm formation at an IC50 of 6.25 µg/mL.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH 3.9 – 7.2
0 7 14

Stability

Optimal stability is estimated within a pH range of 3.9-7.2, based on data from closely related Hedera helix extract. The extract's active triterpene saponins are largely water-soluble, forming micellar solutions, and are typically prepared in water/alcohol systems.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

Specific safety reviews for Hedera rhombea extract by CIR, SCCS, or FDA are unavailable. However, extracts from the related Hedera helix species are generally considered safe in cosmetic formulations when properly diluted. The presence of saponins in Hedera rhombea may induce irritation or allergic reactions in certain individuals, particularly at elevated concentrations, necessitating cautious patch testing for sensitive skin types.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While demonstrating notable *in vitro* antifungal activity, robust human *in vivo* clinical data specifically for Hedera rhombea extract's direct efficacy in broader cosmetic applications remains limited, often relying on inferences from related botanical species.

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