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HDI/PEI-45/SMDI CROSSPOLYMER.

Insufficient Data / ABSORBENT, PLASTICISER

HDI/PEI-45/SMDI Crosspolymer is a meticulously engineered crosslinked polymer that performs multiple functions in precision skincare. It acts as an effective absorbent for both water and oil, while also establishing a continuous film on the skin's surface to enhance product performance and texture.

Summary

Absorbent Film-forming agent Plasticiser Dispersing agent - non-surfactant

Science

Mechanism of Action

This crosslinked polymer operates primarily through its absorbent and film-forming capabilities. As an absorbent, it is designed to sequester excess water and oil, potentially contributing to a mattified skin appearance. Its film-forming property allows it to create a thin, continuous layer on the skin, which can improve product wear, provide a smooth feel, and potentially support ingredient delivery. Additionally, it functions as a plasticiser and a non-surfactant dispersing agent within formulations.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Conflicts

  • Formulators must adhere to good manufacturing practices (GMPs) to rigorously minimize residual hexamethylene diisocyanate (HDI) monomer content to non-toxic levels.
  • GMPs are essential to ensure that low molecular weight polymers (below 1000 Da) are minimized within the final product.
  • If any component moieties are plant-derived, strict GMPs must be employed to limit heavy metal impurities.

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Unknown

The CIR Expert Panel, in its 2016 review, deemed data insufficient to conclude the safety of HDI/PEI-45/SMDI Crosspolymer under intended conditions of use, noting its limited reported use at the time. While the HDI monomer is a known occupational hazard (respiratory issues, dermatitis), the Panel stipulated that proper Good Manufacturing Practices (GMPs) should prevent toxicologically significant levels of residual monomer in cosmetic products. Concerns were also raised regarding potential heavy metal impurities in plant-derived components and the need to minimize low molecular weight polymers (<1000 Da). Key data gaps identified include molecular weight, formulation solubility, dermal absorption, and if absorbed, systemic toxicity data.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While offering potential benefits as an absorbent and film-former, the safety of HDI/PEI-45/SMDI Crosspolymer is currently undetermined by the CIR Expert Panel due to insufficient data, necessitating further research and stringent adherence to good manufacturing practices for its use.

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