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HC YELLOW NO. 2.

Avoid CAS 4926-55-0 / HAIR DYEING

HC Yellow No. 2 is a direct, non-oxidative nitro hair dye. Its small molecular structure allows it to penetrate the hair shaft, imparting washable color without participating in oxidative coloring mechanisms. It is primarily utilized in semi-permanent and permanent hair color formulations.

Hair coloring agent

Science

This ingredient functions by directly diffusing into the hair shaft, imparting a yellow color. As a low molecular weight nitro dye, it bypasses the need for oxidative reactions to deposit color, providing a direct, washable coloring effect.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

HC Yellow No. 2 is primarily a hair dye with no reported skincare benefits, thus the concept of 'dusting' for exaggerated skin efficacy claims is not applicable.


The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

HC Yellow No. 2 exhibits stability within typical oxidative hair dye formulations. However, as a secondary amine, it is susceptible to nitrosation and must not be formulated with nitrosating agents.

Conflicts

  • Nitrosating substances

Safety

CIR Status
Safe with restrictions
Max tested
3%
Sensitization risk Moderate

The CIR Expert Panel deems HC Yellow No. 2 safe in hair dyes up to 3%, a limit based on observed clinical sensitization. European SCCS guidelines are more stringent, allowing a maximum of 1% in non-oxidative and 0.75% in oxidative hair dyes. While not a sensitizer or photosensitizing agent at 10%, sensitization was reported at 3% in repeat insult patch tests (2 out of 98, 1 out of 104 volunteers). It was a minor ocular irritant at 10%. PubChem also notes GHS hazard statements indicating potential for skin (H315, 12% relevance) and serious eye irritation (H319, 49.4% relevance). It is not a developmental toxicant or mutagenic. Formulations must ensure nitrosamine content remains below 50 ppb due to its proneness to nitrosation.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Avoid

HC Yellow No. 2 is a direct hair dye with no reported benefits for skin and presents moderate risks for sensitization and irritation, rendering it unsuitable for typical skincare formulations.


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