Science
Mechanism of Action
This ingredient functions by depositing its color molecules externally on the hair, providing a superficial, non-penetrative coloring effect. It does not exhibit any known mechanism of action or benefit pertaining to skin physiology.
Research
Clinical Evidence
Insufficient-data confidenceN/A
Transparency
Dusting Analysis
No specific data is available regarding the dusting characteristics of HC Red No. 7.
The Formula
Formulation
Stability
Aqueous solutions containing 0.5% carboxymethylcellulose, DMSO, and an acetone/olive oil mixture with HC Red No. 7 demonstrated stability within ±11% of their initial concentration after 2 to 4 hours of storage at room temperature, provided they were protected from light and maintained under an inert gas atmosphere. However, stability data within typical hair dye formulations has not been reported.
Conflicts
- As a secondary amine, HC Red No. 7 is prone to nitrosation, which necessitates careful consideration of potential nitrosamine formation.
- It may contain 2-nitro-benzene-1,4-diamine as an impurity, which is a carcinogen and prohibited in the EU, though current levels are not deemed a safety concern by the SCCS.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has deemed HC Red No. 7 safe for use as a hair dye ingredient under specified conditions and at controlled concentrations, particularly up to 1.0% in non-oxidative hair dyes as affirmed by the SCCS. The FDA also considers 'Red 7' safe in its current applications, with hair dye products containing 'coal tar hair dye' (which encompasses HC Red No. 7) being exempt from certain FDA provisions if labels include mandated caution statements and patch test instructions. Animal studies indicate it is a moderate sensitizer.
Your Skin
Skin Compatibility
Our Assessment
Verdict
While HC Red No. 7 is a recognized hair colorant with established safety parameters for that application, there is a distinct lack of data regarding its efficacy or direct compatibility for skincare purposes, rendering it an unsuitable ingredient for precision skincare formulations.
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