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HC ORANGE NO. 6.

Optional CAS 1449653-83-1 / HAIR DYEING

HC Orange No. 6 is a synthetic direct dye, primarily utilized for imparting an orange color in cosmetic formulations. While it effectively delivers hue, current scientific data does not indicate any active skincare benefits associated with this compound. It is deemed safe for topical application within specified concentration limits.

Cosmetic Colorant

Science

This compound functions exclusively as a cosmetic colorant, imparting a direct orange pigment to products. Research currently available does not document any mechanism of action related to direct skincare benefits or physiological effects on the skin.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

As a cosmetic colorant, HC Orange No. 6 does not offer active skincare benefits; therefore, the concept of 'dusting' to dilute efficacy claims is not applicable. Its inclusion in a formulation serves a purely aesthetic purpose.


The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

HC Orange No. 6 demonstrates stability when stored at ambient room temperature, provided it is protected from light and humidity. The Scientific Committee on Consumer Safety (SCCS) recommends that stability data at its maximum intended use concentration of 0.5% under typical use conditions be provided by manufacturers.


Safety

CIR Status
Not reviewed
Max tested
0.5%
Sensitization risk Low

The Scientific Committee on Consumer Safety (SCCS) has evaluated HC Orange No. 6, considering it safe for use in non-oxidative hair colouring products at a maximum concentration of 0.5%. In vitro assessments showed no skin irritancy, and in vivo tests confirmed an absence of skin-sensitizing potential. While a 20% concentration exhibited potential for eye irritation, this concern is mitigated at the recommended 0.5% use level. Dermal absorption has been found to be very low. It is crucial to distinguish HC Orange No. 6 (CAS 1449653-83-1) from D&C Orange No. 6 (CAS 4372-02-5), which is a distinct, delisted color additive. A specific Cosmetic Ingredient Review (CIR) safety assessment for HC Orange No. 6 is currently unavailable.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Optional

HC Orange No. 6 is an optional ingredient, purely serving as a cosmetic colorant without providing any documented active skincare benefits.


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