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Moumoujus

HABERLEA RHODOPENSIS LEAF EXTRACT.

Valuable / SKIN CONDITIONING

Derived from the 'resurrection plant,' Haberlea Rhodopensis Leaf Extract is a potent adaptogen that significantly enhances skin elasticity and radiance while providing robust protection against environmental stressors. It promotes cellular regeneration and collagen synthesis, leading to a more resilient and youthful complexion.

Summary

Anti-aging Antioxidant Collagen synthesis booster Elastin synthesis booster Skin elasticity enhancer Skin radiance enhancer Hydration support Pigmentation reduction Cellular regeneration Anti-inflammatory Pollution protection Mitochondrial support Glutathione preservation

Science

Mechanism of Action

This extract operates through multiple pathways to rejuvenate skin. It actively stimulates the production of vital structural proteins like collagen (COL1A1, COL3A1) and elastin, which are crucial for maintaining skin firmness and flexibility. Its rich composition of antioxidants, including myconoside, paucifloside, flavonoids, and phenolic acids, provides comprehensive protection against oxidative damage from UV radiation and pollution. Furthermore, it safeguards mitochondrial health, preserves fibroblast morphology, modulates cellular stress responses by maintaining glutathione levels, and possesses anti-inflammatory properties due to components like hispidulin, all contributing to delayed cellular senescence and enhanced epidermal regeneration.

Research

Clinical Evidence

High confidence
Effective range N/A
Optimal

3%

Key findings

  1. 01 In human volunteers, a 3% concentration significantly improved skin elasticity by 300% (P < 0.0002) and skin radiance by 400% (P < 0.05) after 15 days, with these benefits sustained through 30 and 60 days. It also provided 100% protection against UV-induced dermal oxidation (P < 0.01) in human skin biopsies.
  2. 02 In vitro studies on human dermal fibroblasts demonstrated that these concentrations preserved fibroblast morphology, enhanced mitochondrial mass, and upregulated collagen-related gene expression (COL1A1, COL3A1).
  3. 03 In vitro testing revealed that these concentrations were most effective in protecting against oxidative stress induced by H2O2 and maintaining glutathione content closer to normal levels in HeLa cancer cells.

Transparency

Dusting Analysis

Not commonly dusted

The clinically studied concentration of 3% for significant in-vivo results is a robust active level, suggesting that this ingredient is not commonly used at ineffective 'dusting' percentages in formulations aiming for efficacy.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

This extract is water-soluble and is often supplied in a glycerin base. It is a natural, biodegradable ingredient that can be formulated without traditional preservatives.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Haberlea Rhodopensis Leaf Extract is generally considered safe for topical application, with adverse reactions being uncommon. In vitro studies indicate a lack of significant cytotoxic effects at concentrations up to 50 mg/ml and good biocompatibility with minimal genotoxic effects. However, data regarding its topical usage during pregnancy and breastfeeding are limited; individuals in these categories should consult a healthcare professional before use. A patch test is recommended prior to widespread application.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Haberlea Rhodopensis Leaf Extract is a valuable, multifaceted botanical active that significantly enhances skin resilience, elasticity, and luminosity while providing comprehensive antioxidant protection against environmental stressors.

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