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Moumoujus

HABERLEA RHODOPENSIS CALLUS EXTRACT.

Valuable / ANTIMICROBIAL, ANTIOXIDANT, HUMECTANT, SKIN CONDITIONING, SKIN PROTECTING

Haberlea Rhodopensis Callus Extract, sourced from the remarkable resurrection plant, is a potent botanical ingredient engineered to fortify skin resilience. It delivers comprehensive antioxidant protection against environmental stressors while significantly enhancing skin's natural reparative and regenerative capabilities.

Summary

Antioxidant Anti-aging Skin conditioning Skin protecting Elasticity booster Radiance enhancer Collagen synthesis booster Elastin synthesis booster DNA repair enhancement Mitochondrial support

Science

Mechanism of Action

This extract, abundant in myconoside, flavonoids, phenolic acids, and polyphenols, exerts its effects through a multi-faceted approach. It demonstrably stimulates the gene expression of crucial extracellular matrix components like collagen and elastin, leading to increased mRNA levels. Concurrently, it boosts the skin's inherent antioxidant defenses, effectively neutralizing free radicals and preventing their formation. Its biologically active compounds also elevate cellular antioxidant enzyme levels and enhance DNA repair mechanisms, modulating cellular responses to genotoxic and oxidative stress by influencing redox components and cell cycle regulation. Additionally, it helps preserve fibroblast morphology and increases mitochondrial mass, vital for maintaining cellular vitality and skin structure.

Research

Clinical Evidence

High confidence
Effective range N/A
Optimal

3%

Key findings

  1. 01 Provided 100% protection against UV-induced dermis oxidation in human skin biopsies.
  2. 02 Increased skin elasticity by 3 times and skin radiance by 4 times compared to placebo after 15 days of treatment in human volunteers (n=20), with effects sustained over 60 days.
  3. 03 Enhanced mRNA synthesis of collagen VI by 822%, collagen XVI by 928%, and elastin by 144% in peroxide-stressed normal human dermal fibroblasts.
  4. 04 Preserved fibroblast morphology, enhanced mitochondrial mass, and upregulated collagen-related gene expression (COL1A1, COL3A1) in human dermal fibroblasts.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Natural plant extracts can exhibit thermal instability and may degrade during high-heat extraction or formulation processes, suggesting potential heat sensitivity.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) has not specifically evaluated Haberlea Rhodopensis Callus Extract. However, related extracts are generally regarded as safe for topical application, demonstrating good biocompatibility with minimal genotoxic or cytotoxic activity, and adverse reactions are uncommon.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Haberlea Rhodopensis Callus Extract is a valuable botanical offering robust antioxidant defense and significant regenerative benefits for skin elasticity and radiance, supported by strong clinical evidence.

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